Neurohumoral molao oa tsamaiso

Ea bohlokoa mesebetsi ya phelang efe kapa efe Etlare ho latela ka tieo le maemo a potolohileng. Ho etsa sena, o lokela ho nka, silehe, hantle sebetsana le ho nka khato ka matshwao a medumo tloha tikoloho. Sehlopha sohle na ho sebetsa ka kakaretso, e leng 'mele ho sebetsa ka mokhoa o laolehileng le hokahangoa tsela.

Bakeng sa hlopha le go lolamisiwa mesebetsi ea 'mele le bona bo ikarabellang oona tsamaisong neurohormonal. Ho ea ama tsamaiso ea le makala a ka thoko, ho hlokomela mesebetsi e hlophisitsweng, kaofela ha mesebetsi ea bohlokoa ho 'mele. Ka tsela eo botšepehi ba 'mele e bolokoa.

Neurohumoral molao oa tsamaiso taolo e mokgwa oo lisele tsa mmele le mahlahana a mali-jere le litakatso tsa methapo ea kutlo tse sebetsang thulaganyou e le 'ngoe.

Puso tshebetso ya CNS tlas'a tšusumetso ea dintho lik'hemik'hale, e potoloha maling. Ka mohlala, ka sebopeho sa litsoelesa hormonal endocrine le jala e maling e susumetsoa ke taolo ea tsamaiso ea methapo ea kutlo.

Neurohumoral molao oa tsamaiso ke karolo ea bohlokoa ea ho boloka le tumellano hare tsa 'mele le ho go lekalekanyo ka tikoloho kantle. O ile a boela phetha karolo ea bohlokoa ka le thulaganyo ya mesebetsi ho intša go lekalekanyo fisioloji (ka tsela e iketsang ho boloka boemo tieo kamehla ka dithulaganyo le 'mele le lulang li). Neurohumoral molao oa tsamaiso kopanya mekgwa humoral le neural, le bontša ka tsela eo e le mofuta o phethahetseng haholo e sa go lekalekanyo ho feta e mong le ba bona ba ka thoko. Humoral khothalletsa litšusumetso telele taolo. Ka kgokahanyo methapo ea kutlo o entsoe ho etsa bonnete ba sebelisana le ka potlako pakeng tsa libakeng tse fapaneng.

Neurohumoral molao oa tsamaiso ya mesebetsi 'mele ka litsela tse peli. Ke mokhoa oa pele e kenyeletsa le phello e tobileng ea li-hormone kapa metabolites ka CNS lisele. Ka nako e tšoanang na le ho fetola ho excitability ea lisele methapo ea kutlo. Mohlala, carbon dioxide e ka liketso tsa mali ka lisele tse ea tsamaiso ea matšoafo le alimentary tlhotlheletso tsamaiso e khopo a ka cell o etsoa ke lik'hemik'hale ho hlophisoa ha mali. Neurohumoral molao oa tsamaiso o boetse o etsoang ke ketso ea tse fapa-fapaneng, wind- 'mele ka tsela ya dintho mali receptors itseng viscera. Ba qala ho arabela liphetoho ka lik'hemik'hale le khatello osmotic a mangata. Kahoo, ho etsa mohlala, ka kopanelo le lisele tse ea tsamaiso ea ho hema ho phetoho ka dikahare tsa carbon dioxide ho mabota mali sejana chemoreceptors arabela.

The molao oa tsamaiso neurohumoral akarelletsa palo e khōlō ea itseng le nonspecific lihlahisoa metaboliki (metabolites). Tsena li akarelletsa gastrointestinal le dinama tse nyenyane tse-hormone, histamine, neurohormones hypothalamic, e mengata e fapaneng oligopeptides prostaglandins. phallo ea mali le hlaha ka kabo tsa bona ho pholletsa le 'mele. Leha ho le joalo, le itšoare ka e itseng ba bakela feela "sephetho le 'mele" ha ba kena a kopana le receptors bona.

Boemo neural le litsamaiso humoral 'meleng e laolwang ke boemo ba lihlahisoa biologically mafolofolo maro le maro a. Ka radioimmunoassay, immunocytochemistry, histochemistry, ho hlahloba sena ho pharaletseng e sebediswa ultrastructural. Kamehla phetoho ea dikabo ya boleng le ditirisanommogo tsa lihlahisoa biologically mafolofolo nakong bontša le etsang qeto ea reactivity, le molumo oa likarolo bobeli e bohareng le e pheriferale tsamaiso ea methapo ea kutlo, 'me hape ea etsang qeto ea mosebetsi bophelo ba phelang eohle. Dipharologanyo tsa dithulaganyo tsa molao oa tsamaiso ho itšetlehile haholo-holo ka susumetsa ba bang ka ntle le ka litlhoko tsa phelang.