Myeloproliferative lefu: bakang, matšoao, phumano

Myeloproliferative lefu bakang, matšoao, phumano ya e leng tla tšohloa hamorao, etsa sehlopha sa re, khahlanong le tseo ke lesapo moko, ho na le e eketseha tlhahiso ea thrombocytes, erythrocytes kapa leukocytes. Ka palo yohle ho na le mefuta e tšeletseng tsa pathologies.

Overview

Moko oa masapo ke ka tloaelo etsa molokong o mong ka bakoang (immature) liseleng. Ka mor'a nako e itseng ba hōlileng ka ho feletseng, ba tletseng. A seleng ea bakoang ka 'na ba qala ka ho sebopeho sa mefuta e' meli ea lintho tse: nomoro ya lymphoid le myeloid liseleng. lisele tse Immature ke litšoantšo bakeng sa sebopeho sa leukocytes. Har'a thepa ea motheo ea letoto la lihlooho tse myeloid etsoa:

• Erythrocytes. Ba tsoele oksijene le limatlafatsi tse ling dikgokelo ho makala 'me lisele tse.
• Leukocytes. likarolo tsena ke le boikarabelo ba ho khanyetso le pathologies tse ling a tšoaetsanoang.
• Liplatelete. lisele tse tsena Thibela tsoa mali, foromo clots.

Pele ho phetoho ka lisele tse khubelu tsa mali, lisele tse tšoeu mali kapa liplatelete, thibela lisele tse hlokang ho ea ka methati e mengata. Ha jwale, lefu myeloproliferative, e kholo chelete ea lintho tse bonahalang ho tloha Ho thehoa ke mefuta e 'ngoe kapa ho feta lisele tse thehoa. Ka tloaelo ho bolwetse setsi butle lekana le eketseha likarolo feteletseng mali.

tlhophiso

Mofuta o ka ba le lefu myeloproliferative itšetlehile ka ka tjhelete e ya erythrocytes, li-platelet, kapa leukocytes. Maemong a mang, 'mele o ke tshwaileng e feteletseng ea metsoako ea mefuta ho feta feta a le mong. Bolwetse e arotsoe:

• Foleng neutrophilic kankere ea mali.
• Polycythemia.
• Foleng myelogenous kankere ea mali.
• Bohlokwa thrombocytopenia.
• Idiopathic (sa foleng) myelofibrosis.
• Eosinophilic kankere ea mali.

sethaleng pathological

Boloetse bo sa foleng myeloproliferative ka fetoloa kankere ea mali a hlobaetsang. boemo ena e tšoauoa ka e feteletseng ea lisele tse tšoeu tsa mali. Foleng myeloproliferative lefu ha le na itseng staging sekemeng. mehato phekolo e itšetlehile ka mofuta oa bolwetse. Mabapi le litseleng, ho lefu myeloproliferative ka etsahala 'ngoe ea litsela tsena tse tharo:

• Tsoele pele ho mela ka lisele tse ling. Tabeng ena, kankere ata ho pota-potileng likarolo ka bophelo bo botle, ho otla ba.
• Lymphogenous tsela. lefu Myeloproliferative ka phunyeletse ka tsamaiso lymphatic le tšelang lona aba ka lisele tse ling le litho tsa ka hare.
• Hematogenous tsela. Lisele tse malignancy phunyeletse ka methapong le methapong hore fepa lisele le litho tsa ka hare.

Ha ho ata ha lisele tsa hlahala, mohlomong eaba ba etsa e ncha (mahareng) lihlahala. Tshebetso ena o bitsoa metastasis. Mahareng ho lihlahala mathomo, ke mofuta o tšoanang oa ho kankere. Mohlala, ho na le ke ho ata ha lisele tse leukemic ka bokong. Ho fumana likarolo hlahala. Ba bua ka kankere ea mali, e seng bakeng sa kankere bokong.

lipontšo tsa bolwetse

Joang lefu myeloproliferative? Matšoao a mafu a tse latelang:

• boima ba 'mele, ho ipolaisa tlala.
• Mokhathala.
• Mala boemong bo sa thabiseng le boikutlo ba ho itima lijo lijo ho tlala. Last halefile atolositsoeng spleen (splentomegaliey).
• Predisposition ho tsoa mali, ho longoa, kapa matšoao a thrombosis.
• Phytoteratology akheha.
• Kopanetsoeng bohloko, ho ruruha, halefile gouty ramatiki.
• Ringing litsebeng le.
• Soreness ka le letšehali ka holimo quadrant tsa mpa le letšehali ka mahetla, e leng ka lebaka la ho ruruha kapa infarction ea spleen ena.

phuputso e entsoeng

Myeloproliferative ho hloka taolo le hore mali a lemoha ka lebaka la sephetho laboratoring. Phuputsong e akarelletsa mesebetsi e latelang:

• Hlahloba mokuli. Tabeng ena, setsebi sa rerang boemo kakaretso bontša matšoao a bolwetse (ho ruruha, ho etsa mohlala), hammoho le lipontšo, ho ne ho se motho ea ka bophelo bo botle. ngaka boetse a kōpa ka bophelo ba mokuli, mafu a le mekhoa e mebe, ho laela.
• Atoloswa Kla. mohlala mali o etsoang ho tsoa ho bona hore:
  
  - palo ea li-platelet le lisele tse khubelu tsa mali;
  - karo-karolelano 'me palo ea leukocytes;
  - boemo ba haemoglobin;
  - molumo ea eona e lula lisele tse khubelu tsa mali.

• Aspiration le masapo moko biopsy. Nakong ea Tsamaiso, e leng teteaneng sekoti nale e hlahiswa ka sternum kapa iliac masapo. mellwane ena lumella u ho nka lesapo moko sampole le dinama tse nyenyane tse hammoho le mali. lintho tse bonahalang tse e hlahlojoa ka ho ya microscope bakeng sa ho ba teng ha lisele tse sa tloaelehang ka ho eona.
• Cytogenetic hlahlojoe. Tsamaiso ena lumella u ho lemoha liphetoho chromosomes ena.

Foleng myeloproliferative lefu: Phekolo

Ho fihlela joale, ho na le phekolo lefu tse 'maloa. Le 'ngoe kapa khetho e meng e khethiloeng ho itšetlehile ka boemo ba mokuli le liponahatso hore a tsamaee le lefu myeloproliferative. Ho phekola ka laolwa tekanyetso - proven ikwetlisetse, kapa liteko. Khetho ea bobeli ke ho ithuta le ho sebelisa ho bolela e sa tšoaneng e ncha.

phlebotomy

Tsamaiso ena e noa mali ho tswa ho mothapo ka. lintho tse bonahalang tse ka nako eo o ile a romela ho skeletal and analysis tloaelehileng. Maemong a mang, phlebotomy laetsoeng ho bakuli ba na le boloetse ba lefu myeloproliferative. Phekolo tabeng ena o ile a laela ho fokotsa palo ea erythrocytes.

platelet apheresis

Mokhoa ona e tšoana le ea pele. phapang ke hore ho na le o etsoang ho tsoa ho tloswa ha liplatelete ena e eketsehileng ho sebelisa thepa e khethehileng. Mokuli o le mali e feta har'a kgaoganyo ena. O nang le li-platelet. "O ile a hloekisa" mali khutlela mokuli.

tšelo

Tsamaiso ena ke tšeloe mali. Tabeng ena ho tloswa ea ba bang ba likarolo tse ling. Ka ho khetheha, ho ba le mamello sebakeng sa lisele tse bona timetsoa le senyehile gets tšelo ea lisele tse tšoeu tsa mali, lisele tse khubelu tsa mali le liplatelete.

phekolo ea lik'hemik'hale

Mokhoa ona akarelletsa tšebeliso ea lithethefatsi cytotoxic. bohato bona o ikemiseditse ho ho timetsoa ha lisele tsa hlahala kapa slowing kgolo ya lihlahala. Ka molomo, intravenous kapa intramuscular sebelisa lithethefatsi, metsoako bona a sebetsang a phunyeletse ka ajoa systemic, felisa likarolo pathological. Sena se bitsoa systemic chemotherapy. Lewa Regional ke selelekela se bolela ka kanale lesapo la mokokotlo, ho ameha lekala kapa mohohlo mmeleng toba.

phekolo mahlaseli

Kalafo o etsoang tsoa sebelisa phahameng maqhubu a x-ray kapa mahlaseli tse ling. Mahlaseli phekolo ka fihlella ho felisoa ka ho feletseng ea lisele hlahala le liehe kgolo ya lihlahala. Ka mokhoa ona, ka mefuta e 'meli ea phekolo. mahlaseli External phekolo ke ho pepesehela ea unit trust e, teng haufi le mokuli. Ha e ka hare ea tlatsang thulaganyou e e etsoang ke ntšang mahlaseli a kotsi dintho linale, catheters, methapo, tse ka nako eo tshelwa ka kotloloho ka hlahala kapa ka lisele tse ka teng ho pota eona. Eo mokhoa tla sebelisoa setsebi, ho itšetlehile ka tekanyo e sa malignancy ya tshebetso. Bakuli ba na le boloetse ba myeloproliferative boloetse mali e irradiated, e le busa, sebaka spleen.

Phekolo ea lik'hemik'hale le transplantation ea lisele

mokhoa ona oa ho kalafo ke sebelisa lithethefatsi ka tekanyetso e phahameng le ho tloswa ameha antitumor ketso ea lisele tse ncha. likarolo Immature di tswa ho mofani kapa mamello le hoammeng. Ha ke qeta, chemotherapy, e hlahiswa ka 'mele tse bonahalang li bokeletseng. Dipopontshwa lisele tse qala hōlileng ka ho feletseng le ho susumelletsa sebopeho sa lisele tse ncha mali.

nako hlaphoheloa

Mora kalafo, ho ba le mamello ba lokela ho bona ngaka ya hao ya kamehla. Ho hlahloba katleho ea phekolo 'na ha hlokahala hore a tsamaise letoto la mekgwatshebetso ya ho sebelisoa neng pele motho o thontsoe le. Ho latela liphello, etsa qeto ea ho tsoela pele, ho phethoeng kapa phetoho ea phekolo Melao. Ba bang ba dipatlisiso lokela ho a pheta ka metlha, esita le ka mor'a phethoa tsela phekolo. Ba dumella ho hlahloba tshusumetso ya liketsahalo le khona ho utloa khutlela mokhoeng.