Mefenamic acid e

"Mefenamic acid e" - lithethefatsi ho pharaletseng sebelisoa ka arthrology, kalafo ea mafu a tšoaetsanoang ba hlabang tlhaho, Fokotsa matšoao a boko.

lithethefatsi ena ke ea sehlopha sa dintho diokobatsi fenamates - dintho le-ba khahlanong le a hlabang sebediswa. "Mefenamic acid e" o behile mekolokotoane eo ka boeona e ka e babatsehang antipyretic le analgesic.

Lithethefatsi na le mochine o rarahaneng oa ho nka khato e akarelletsa ho ba le seabo ka ho toba ka liphetoho e hlabang. "Mefenamic acid e" (a sebetsang a ntho) ho fokotsa tswakana ya dintho itseng (mediators), tse akarelletsang prostaglandins, kinin, serotonin. Ho phaella moo, e haholo ho fokotsa mosebetsi oa lysosomal enzyme proteolytic, e sebetsang ka kotloloho ka mekhahlelo e tse peli pele ba ho ruruha: exudation, keketseho. litla tse ling tsa lithethefatsi ena e kenyeletsa: ho tsitsisoa tsa lera la seleng e le ultrastructures protheine, fokotseha vascular e lumellang metsi ho kena le ho ruruha ea lisele tse anngoeng ke likoluoa, ho eketsa mosebetsi oa serotonin, e ile ea eketseha ho hanyetsa ea lisele, tlhotlheletso ya dithulaganyo nchafatso. Analgesic lithethefatsi e le hantle ke eena ea ka ho toba e le hantle ka bohareng mochine oa bohloko nahanela, hammoho le ea moo bohato ka a hlabang tsepame. thepa Antipyretic di amanang le e tobileng thibela prostaglandin tswakana, litla ka setsi thermoregulatory ka bokong. Tšobotsi e 'ngoe ke ho susumelletsa ho hlahisa interferon, eo ka ho toba kgothaletsa le thepa proliferative tsa ntho mafolofolo.

Mefenamic acid e na le ho lekaneng phahameng absorption coefficient. Ea mahloriso lebetsoeng le e fihlellwa ka mor'a lihora tse peli ho isa ho tse 'nè ka mor'a lenyalo. Boemo ba lithethefatsi mali ke kamehla tekanyo e lekanang ya ho lethal dose lona fumaneng. Tsamaisa ka maling ya moriana le hlaha ka ho tlama ho albumin. The halofo bophelo ba boleng bo le mafolo-folo ke lihora tse tharo. Hoo e ka bang mashome a tšeletseng ba etsang liphesente tse e excreted ka moroto le foromo hoo e batlang e unaltered, mashome a mabeli a metso e mehlano - le mantle ena.

"Mefenamic acid e" o na le a manyenyane lohle lekane ka mosebetsi, e leng e hlalosoa ka ho plurality tsa litla hore e fetolela le moemeli a sebetsang. mafu Major, matšoao a eo ka sebetsana hantle ea lithethefatsi ena ke nonspecific polyarthritis, a hlobaetsang le rheumatism, neuralgia, myalgia, arthralgia, ankylosing spondylitis, a batang, periodontitis. moriana o ka o boetse o ne a rerile hore kokotang hlooho, meno bohloko, feberu sethoathoa, matšoao a mafu a matsatsing.

Bakeng sa "acid e mefenamic" Ho na le contraindications tse 'maloa, tse khōlō tsa eo ke hypersensitivity teng duodenal lefu seso le mala, gastrointestinal hlabang mafu ea mali, a liphio. Nakong ea bokhachane, diabolololo lokela ho lekanyetsoa feela ka ho sebelisa lithethefatsi ena.

Kozalana le tse ling lihlopha tsa lithethefatsi - mong ho feta karolo e, e leng ke ho le khetholloang ka mefenamic acid e. Tataiso ho ba lokisetsa ho ea e hlalosang ka ho qaqileng tsohle liphetoho khoneha le mathata. Ha ho kopana le "Analgin" le salicylates ntlafatsoa-ba khahlanong le a hlabang sebediswa. Lithethefatsi hape eketsa prothrombin nako ha nka anticoagulants.

Liphello tse khōlō-morao, le nang le asiti mefenamic, ke ho tswa ho ho hloka taolo gastrointestinal talima ka eona dilenaneo le meferefere dyspeptic. Ka tšebeliso nako e telele tsebeliso ea lithethefatsi ho ka ntshetsa pele haemolytic khaello ea mali mofuta.