Hyperplasia - ke eng see? Glandular endometrial hyperplasia. Lobular hyperplasia tsa endometrium ho

Hyperplasia - boemo bo tsejoang ka ho eketseha ha palo seleng ea ka dinama tse nyenyane tse, kapa lekala (ntle le bakeng sa lisele hlahala). Le ka lebaka la tsoelo-pele ea lefu lena ke hlahala kapa le keketseho tšoauoa ka boholo 'mele.

Develops hyperplasia ile ka tse ngata tse litšusumetso tse amang boikatiso ea lisele Stimulating. Kahoo, a ka mo lakalisa ntshetsopele ya antigenic susumetsa ba bang dintho oncogenic, khōlo ea buellang kapa ke tahlehelo dinama tse nyenyane tse, bakeng sa eng kapa eng eo lebaka, lekala kapa karolo ya dinama tse nyenyane tse. Fisioloji hyperplasia - e sprawl nakong ea bokhachane le mammary epithelium, ka ponahalo ea hyperplasia glandular pele kapa nakong ea ho ilela khoeli, 'me tse ling tse liponahatso tse tšoanang.

E le mohlala, hyperplasia, tsoelang pele maemo pathological, ka ho bitsoa ho eketseha ha thepa ea motheo mehaho bakuli mefuta e itseng ea khaello ea mali myeloid dinama tse nyenyane tse. Ho phaella moo, dithulaganyo hyperplastic ka etsahala ka lymphoreticular nodes dinama tse nyenyane tse lisele tsa mmele, e-ba le karabelo ba mmele ka spleen e, tabeng ea mafu a tlhaho a tšoaetsanoang.

A mefuta e fapaneng ya liforomo

Ka moriana, ho na le mefuta e 'maloa tsa motheo:

1. Fisioloji hyperplasia. Dinama tse nyenyane tse kgolo ya le hlaha, e leng mesebetsing kapa ba nakoana. Mohlala, hyperplasia tsa mammary litsoeleseng nakong diabolololo kapa ho ima.
2. Pathological hyperplasia. Ka lebaka la lintlha tse 'maloa precipitating etsahala kgolo ya dinama tse nyenyane tse.

Ho phaella moo, le maloetse ka 'na ba tsepamiso, diffuse le polypous:

1. Ha ho na le ke mofuta o mong o hlakileng oa tsepamiso thulaganyou e diriswa ka mokgwa wa dikarolo ka bomong.
2. Ka diffuse hyperplasia palo yohle lera ameha feela.
3. Bakeng sa foromo polypous tšoauoa ka boela la atolosoa lekane ya thepa ea motheo e tlohang. Tabeng ena, hyperplasia a ka mo lakalisa ntshetsopele ya educations jele setsi le cysts.

Diffuse hyperplasia ya thyroid tsoelesa

lefu lena le hlaha ha compensatory itsoara joang ka khaello thyroid iodine litareng e. Poleloana e reng "diffuse" e bolela hore bolwetse ama 'mele kaofela: ke ho eketseha ha boholo ba eona ka lebaka la ho ho ikatisa lisele tse ea tšoelesa ea senya e le hore ho boloka ho secretion hormone thyroid e ntšetsang pele metabolism, ho matlafatsa ho absorption ea oksijene tšehetsa boemo ba matla.

Thyroid iodine litareng e hlokehang ho boloka mosebetsi lona hormonal. Ho haella kapa ho ba sieo ha a iodine litareng e khothalletsa keketseho ea lisele kankere le ka o ile fella ka ho se sebetse.

adrenal hyperplasia

Lefu lena le ka ba diffuse kapa nodular. E tsamaea le ho tsoela pele ka mosebetsi adrenal dinama tse nyenyane tse tabeng ea dihlahala pineal le lefu Cushing e. Ho batho ba baholo, ka foromo ena ea hyperplasia, haholo-holo setse-neha, le ho ithuta ho tsa ultrasound ke ho le thata haholo ho amohela le ho hlola ka ho bua ka taba ea ho ithuta ka MRI le CT.

Ka linako tse ling diffuse hyperplasia adrenal e tsamaea le eketseha coercion ha lula litsoelesa ho tloaelehile ponahalo ea - ka sebopeho sa dibopeho hypoechoic, pota-potiloe ke dinama tse nyenyane tse nonneng. Tabeng ea hyperplasia nodular ka "triangolo ea mafura" ho ka bonoa ho potoloha, homogeneous hypoechoic sebopeho. Ba thata ho khetholla ho tloha ya adenoma ka ultrasound tse setšoantšong.

Ea tšoelesa ea senya - nang kotsi prostatic hyperplasia

Ho 85% ea batho ba baholo ho lilemo tse 50 e ka tlasa lefu lena. Nang kotsi prostatic hyperplasia e tšoauoa ka sebopeho sa ea tšoelesa ea senya maqhutsu tse seng kae tse nyenyane (kapa e mong) eo ata ka butle-butle qala ho tsoela pele urethra, e leng o ile etsa hore bothata ba ka ho ntša metsi.

Lefu lena le ha a bake metastasis, hore ntlha e khethollang bakeng sa kankere ea hae ea tšoelesa ea senya, kahoo, ho e bitsoa nang kotsi prostatic hyperplasia. Tabeng ena, ho na le ha ho na le lisosa tse hlakileng le atisa ho amahanngoa le menopause motona.

endometrium uterine

Hyperplasia - e nang kotsi keketseho e le botenya le bophahamo ba modumo ea uterine lera. Ho ka 'na etsahala ka lebaka la ho ikatisa e le glandular le lisele tse ling tse dinama tse nyenyane tse. Lefu lena le ka etsa hore ho qhala tsa mosebetsi tshebetso ya endometrium le (conceiving mathata, phytoteratology menses).

Tlas'a maemo a tloaelehileng, ho endometrium e ntse e hōla tlas'a ketso tsa estrogen bananeng, ka nako potoloho pele, le tlas'a tšusumetso ea progesterone nakong ea bobeli ea potoloho e thibile. Ka bolwetse ea khōlo endometrial e sa laoleheng, e le ea nang le bokhoni ea hapang bobeli kaofela hare selateng le likarolo motho (lobular hyperplasia).

Mefuta e sa tsoaneng ya hyperplasia endometrial

Ho ea ka predominance likarolo tse itseng ka endometrium hōla lokolloa:

1. Glandular hyperplasia. litsoelesa Endometrial e hōle ka ho feteletseng.
2. Polypoid hyperplasia. Ea kgolo ya patchy tsa endometrium, e leng glandular, glandular-fibrous le fibrous ka tlhaho. Ea mofuta ona e hyperplasia seoelo fetoha bolaeang, empa ka sebeletsa e le motheo bakeng sa ntshetsopele ya mafu gynecological.
3. Adenomatous hyperplasia le ho ba teng ha ea lisele atypical, premalignant. Ka degeneration ena ka hyperplasia bakeng sa kankere mofuta ona a ka finyella ka 10%.
4. Cystic glandular hyperplasia. cysts tšoelesa le hōle ka e tšoanang.

lisosa tsa

Ho fihlela joale, sesosa se ka sehloohong sa lefu lena ke fetang ho hloka mong ka progesterone maemo fisioloji estrogen bananeng. Joalo boemo ba motho ba ka etsa hore:

1. Phetoho lilemo ka tlōlo ea metabolism hormonal le lelemela hormonal.
2. Basali botenya.
3. Polycystic Ovary Syndrome.
4. menopause.
5. Fumana litokisetso nang estrogen bananeng, ntle ho ho fumana progesterone.

hangata haholo, endometrial hyperplasia (maikutlo ho tswa ho litsebi li tiisa sena) le hlaha ho basali ba pele menopause ka basali ba bacha nulliparous.

Comorbidities, eketsa le pontšo ea hyperplasia, ho nkoa e le bothata bo ka tšoelesa adrenal le letsoele, lefu thyroid, lefu la tsoekere mellitus tsa mefuta bobeli, hammoho le kgatelelo ya madi. Ke ntshetsopele ya hyperplasia ka boela etsa hore lintlha tse kang tsena:

1. Lefutso tsa mafu genital.
2. Adenominoz.
3. uterine fibroids.
4. Ho ntša mpa le curettage.
5. Hlabang dithulaganyo genitalia.

Mabaka a bakeng sa ntshetsopele le ho mefuta e meng ea glandular endometrial hyperplasia

Main bakang glandular hyperplasia:

1. Anovulation.
2. Nona haholo.
3. Ho ba teng ha cysts follicular.
4. Menopause.

Ho boetse ho na le kotsi ya lefu phehella follicle, glycemia le granulosa seleng ea dihlahala.

Ho hloka kalafo le lieha phumano ya lefu lena e le tletse lintho tse ngata ka liphello tse kotsi, joalokaha ntshetsopeleng ya kankere endometrial. Hangata ho kotsi ke basali ba khathatsoang ke atypical hyperplasia ademonatoznoy le basali ka nako e ka mor'a menopause. Ho tsepamiso le diffuse hyperplasia - e precancerous mofuta o mong oa lefu lena.

mefuta e meng ea hyperplasia endometrial li nkoa e matla ata ha epithelium glandular, cystic litsoelesa dilated le glandular-cystic hyperplasia.

le matšoao

Maemong a mangata, hyperplasia tsa litsoelesa le hlaha ka ntle ho le matšoao a ikhethang ea tleleniki. Ka liponahatso ena tloaelehile hore batho ba li nkoa dysfunctional uterine mali e bakoang ke irregularities matsatsing (menses lieha). mali Sena se ka ba ka bobeli profuse le ka nako e telele, 'me ho lahleheloa ke mali a - bo boima kapa e leka-lekaneng. Ka lebaka leo, ho ntshetsa pele matšoao a anemic: ho lahleheloa ke takatso ea lijo, mokhathala, bofokoli.

Pakeng tsa nako e ka bonoa spotting. hangata ha ho ho basali ka lebaka la ho mabokosana anovulation kgaolela basadi thari. Seo ke sona sa le lebaka la ho kgaolela basadi thari e le leeto la ho ea ngaka e neng e ile hlahloba lefu lena. Har'a matšoao le ka boela ile a hlokomela bohloko sebakeng sena ka tlaase mpeng.

Diagnosing glandular hyperplasia ka etsoa ke dilatation le curettage, eo o etsoa hang-hang pele ho ilela khoeli. Haholo atisa ho sebelisa ka phumano ya tsa ultrasound, le hysteroscopy.

lobular hyperplasia

Lobular hyperplasia (litsebi ulasan pelanggan bontsha bopaki ba hona) ka sokela kankere le ho kgaolela basadi thari. Length of phatlalatsa kapa asymptomatic khona ho lemoha lefu lena feela nakong ultrasound tse kapa ho hlahloba ka gynecological.

Lobular hyperplasia hangata develops hamorao maloetse hormonal, ka mor'a ho fetiswa ha mafu somatic le ho ntšoa ha limpa kapa khahlanong le semelo sa hyperplasia tsa mofuta o glandular.

Lobular hyperplasia tsa epithelium uterine e fumanoa ka lebaka la matšoao a latelang:

• tsoa mali ka mor'a cessation ea ho ilela khoeli;
• acyclic kapa cyclic irregularities matsatsing.

Kalafo ea lefu lena ka litsela tse peli tse ka sehloohong:

1. Medical mokhoa - ka thuso ea lithethefatsi e khethehileng, ho akarelletsa mofuta hormonal.
2. Ho buoa kapa sebetsa mokhoa - ka fala le uterine cavity.

Phumano ya hyperplasia endometrial

Motheo bakeng sa fumanoe lefu lena ke ho hlahloba ke gynecologist ka, bakeng sa phuputso karaoke le laboratori ea.

Ka sehloohong fumanoe mekhoa e kenyeletsa:

1. Ultrasound maemong hlahloba ka popelo le appendages bosaling fatang.
2. Hysteroscopy le biopsy exemplar ho itlhahloba histological.
3. Diagnostic fala le uterine cavity.
4. Haeba ho hlokahala, hlakisa le mofuta oa hyperplasia tshwerweng aspiration biopsy.

E mong oa ho etsa lipatlisiso bohlokoa ka ho fetisisa le laboratori eo ke tlhaloso ya maemo serum ho kopanela liphate li-hormone le thyroid le litsoelesa adrenal.

Ke habohlokoa ho hopola hore mofuta ofe kapa ofe hyperplasia hloka phumano e nepahetseng le ho hlokomela lintho tse bakelang 'nete, e leng ile sa etsa hore ho eketseha ha dinama tse nyenyane tse.

kalafo

Haeba u ne u na le boloetse ba hyperplasia, kalafo e etsoa hang-hang. mokhoa o kgethile thehiloeng matšoao a lefu lena le lilemo tsa ba le mamello.

Tsela e atlehang ka ho fetisisa - tekotshupo curettage kapa hysteroscopic tlosa baprocedure endometrium diffuse.

Haeba tshebetso kalafo ke selotlolo tlhaku, pele ho tsohle, ho phetha tshohanyetso kapa elective fala. Ke ho retelehela ho mothofatso pele ha anemizatsii kapa tsoa mali.

Hang liphello sobotta li amohetse, setsebi sa ka abela ea mekhoa ea phekolo e tse latelang:

1. A le lilemo li 35 lilemo tse prescribers ba khahlanong le lōna ba gonadotropin.
2. IUD "Mirena" le progestins.
3. lithethefatsi progestin ( "Djufaston", "Utrozhestan") ba abeloa ka nako ea bobeli ea potoloho ena.
4. Ka morero oa ho bao e seng sebelisa mehaho setopong tsoa mali ka Banana bao ke sa le monyenyane, li lumelloa ho sebelisoa ka tekanyetso ka toka khōlō ea lithibela-pelehi molomo.
5. Motswako molomo lithibela-pelehi ( "regulon" "Yaryna" "Janine") o abetsoe ho likhoeli tse 6 le baeti ba fihlelang ho oa potoloho tloaelehileng.

Litokisetso tse boletsoeng ka holimo, bopa le phello e tšoanang le menopause, empa reversible.

Mora fala ntse ka likhoeli tse tšeletseng leihlo, 'me ha ho na le ke boipheto mefuta adenomatous hyperplasia, ho bontša ho tlosoa ha pōpelo ea. Ha mefuta e meng ea relapsing le inefficiency mekhoa ea phekolo e tse ling tse itseng timetsong maiketsetso tsa endometrium (ablation).

Itse'ng le mathata

The complication kotsi ka ho fetisisa tsa hyperplasia endometrial - ke phetoho lona ka kankere ea popelo e. Leha ho le joalo, tsoa mali ha tlase kotsi le recurrences le tsoelo-pele ea ho kgaolela basadi thari le khaello ea mali.

Maemong a mangata, e itse'ng e tšoanelang: ka lebaka la ho buuoa le prima lithethefatsi bakeng sa dikgwedi 6-12 ke ke ka ho feletseng phekola lefu lena.

thibelo

Le mehato bohlokoa ka ho fetisisa tsa ho thibela hyperplasia endometrial - ke ho thibela maemong a sithabetsang, e loana ntoa e chesehang ea mafolofolo khahlanong nona haholo le ho hang-hang ho phekoloa mafu a ea matsatsing. Hape ke habohlokoa haholo nakong gynecological hlahloba basali.

Ka linako tse ling mocha banana ba setsebi ka kgothaletsa bakeng sa thibelo ea lithethefatsi hormonal hore fokotsa menyetla ea hyperplasia endometrial le kankere. mosali ofe kapa ofe lokela ho hlokomela hore ka ketsahalo ea mali uterine lokela hang-hang a bale setsebi. Hopola hore phekolo ka nako e loketseng ho ngaka e tla re thusa nakong e tlang ho qoba boholo ba mathata a ba.