Medicine "primidone": litaelo bakeng sa ho sebelisoa le ditshwaelo

Morao-rao lik'hamphani meriana hlahisa palo e khōlō ea lithethefatsi antiepileptic. Tsela ea ho utloisisa a sa tsoaneng a lithethefatsi? Ho etsa sena, retelehela ho profesionalce nang le phihlelo. O tla kgona ho khetha bakeng sa u moriana atlehang ka ho fetisisa, e leng se tla re thusa hore endowment bohlokoa ba le mamello.

Ka ho fetisisa ratoa antiepileptic lithethefatsi har'a bakuli le lingaka ke meriana "primidone". Litaelo tsa tšebeliso ea lithethefatsi o ile a re, hore ho lokolloe foromo le thepa ea eona li tla fanoa e nyenyane hamorao.

Sebopeho, sebopeho le ambalaji

Reka moriana "primidone" e ka ba ka mefuta e 'meli e fapaneng. Ho fumaneha e le phofo le e tsa phutheloa ka mokotleng o kopanetsoe-lera polasetiki le lebokose lebokoso, ka ho latellana. Ho boetse ho bolela o ka reka ka mokgwa wa matlapa ka dipakete blister le mabokose.

The a sebetsang a motsoako ka lithethefatsi ena nka khato primidone. Hape ho kenyelletsa ditokiseletso malandi (ho itšetlehile ka liforomo ho lokolloa).

Ketso ea moriana

ke pheko bakeng sa "primidone" ke efe? Litaelo bakeng sa ho sebelisoa li bontša hore lithethefatsi ena antiepileptic. Ho tlatsetsa phello bonolo hypnotic, empa hape ho fokotsa excitability ea methapo ea kutlo eo ba sebakeng setsa tsoeroe ke sethoathoa.

thepa life tse ling tse sa tlholeho ka moriana o "primidone"? Bohlokwa tremor ha e felisa mali mahloriso ea 12 .mu.g / ml tse.

thepa kinetic

Lithethefatsi "primidone" (matlapa le phofo) ka toka ka potlako 'me hoo e ka bang ka botlalo ananelang pampitšaneng gastrointestinal. Ea mahloriso phahameng ka ho fetisisa ya moriana fihlellwa ka mor'a lihora tse tharo. The bioavailability ea lithethefatsi ena ke 90-100%. Maling e tlama ho liprotheine hanyenyane (hoo e ka bang 20%).

Halofo ea bophelo ba moemeli ena ke dihora tse 7-15.

Ka sebete, le moriana o ke mokhoa o sa fellang sokolleloa phenobarbital (ka 20%) le feniletilmalonamid. metabolites tsena rua mosebetsi antiepileptic. Ba excreted ke liphio.

mali mokuli a se ke ho hlokahala hore a lule a phekola lithethefatsi mahloriso ea 12 ug / ml tse. Ho litsupa tsena kenya letsoho hore ho slowing sethoathoa. Ha mefuta e meng ea lefu la sethoathoa (mohlala, batho bao e seng convulsive mefuta e meng ea sethoathoa polymorphous le tse ling), phello ea phekolo e sa kamehla fihlellwa. Tabeng ena, ho phekola rarahaneng.

Bontšang bakeng sa tshebediso ya moriana

Maemong a mang, ho ba le mamello e hlophisitsweng meriana tse kang "primidone"? Reviews ba tlalehile hore sesebelisoa sena ka tsela e atlehang tšoarang sethoathoa ea tšimoloho e sa tšoaneng, hammoho le a leeme le generalized sethoathoa. Le ntshetsopele ya tsepamiso, myoclonic le akinetic sethoathoa moriana ona sa sebetsa.

Contraindications ho meriana

Maemong a mang, u se ke ua laela meriana "primidone"? Litaelo bakeng sa ho sebelisoa ea tlaleha hore e se e hanetsoeng ho sebelisa ho bolela ho ba teng ha ka hypersensitivity (ho akarelletsa le barbiturates), hammoho le khaello ea mali, sebete le ho hloleha liphio, bokhachane, mahlaseli a kotsi le kanyeso.

Medicine "primidone": litaelo tsa tšebeliso

Ka seo litekanyetso li behoa e balletsweng ya lithethefatsi re hlahloba? E nkiloe ka molomo mora tshebediso ya lijo ka e le 'ngoe e mong oa nako e lethal dose ea 125 mg,. Ka mor'a moo, e mong le matsatsi a mararo, o ile a re palo ea lithethefatsi ea eketseha ka ba 250 mg, bakeng sa bakuli ba batho ba baholo 'me a 125 mg, bakeng sa bana ba fihla lilemong tsa 9.

phekolo ena e tsoela pele ho fihlela sephetho batlang.

The lebetsoeng le letsatsi lethal dose bakeng sa bana ke 1 g, (ka mekhahlelo e 'meli) le batho ba baholo - 1.5 g,

litla-morao

Ka bomalimabe, pele re antiepileptic lithethefatsi hangata e etsa hore liphello tse sa rateheng. Tsena li akarelletsa boroko ka tsela e feteletseng, ho tšoaroa ke hlooho, molikoalikoane, ho tšoenyeha lethargy, ho nyekoa ke pelo, khaello ea mali, ho hlatsa, leukopenia, kulisa, le lymphocytosis.

seoelo haholo a sebetsang a moriana o ka etsa hore nystagmus, ataxia, "lupus" lefu, liphetoho psychotic, arthralgia, megaloblastic khaello ea mali, 'me tšebeliso ka nako e telele - lithethefatsi itšetleha.

maemo a ho overdose

Noa tekanyetso e khōlō ea lithethefatsi e ka etsa hore le matšoao a kang ho tsekela, ataxia, ho nyekoa ke pelo, le ho tepella maikutlo ea bohareng tsamaiso ea methapo mosebetsi. Bakeng sa kalafo ya maemo a joalo le mamello e hlatsoa mala, butswe mashala le kalafo bontshang matshwao.

Sebeletsana le lithethefatsi tse ling

Ho lokisetsa "primidone" sehlahisoa potentiates phello ea cyclophosphamide, methotrexate le sulfonylureas hammoho le hypnotics. E boetse e eketsa metabolism, eketsa mosebetsi oa microsomal sebete enzyme, ho fokotsa liphello tsa corticosteroids, acetaminophen, li iss pyar, tricyclic antidepressants, anticoagulants, "Chloramphenicol", "DTIC", "Cyclosporin" cardiac glycosides "disopyramide", "Levothyroxine", "Doxycycline "" theophylline "," metronidazole "," Quinidine "," mexiletine "oa vithamine D,« fenoprofen, "caffeine" Aminophylline "le" oxtriphylline. "

O ne a nka moriana o kgothaletsa CNS tepella maikutlo hammoho le ho bolela ho bohareng depremiruyuschim bohato le joala.

Lithethefatsi "se entsoeng ka amphetamine" liehisa ho absorption ea phenobarbital.

Hammoho le inhibitors k'habone anhydrase Amplified osteopenia.

Sena se fokotsa absorption ea griseofulvin moemeli hore ho fokotsa mosebetsi lona antifungal. E boetse e kgothaletsa liphello tse chefo "enflurane", "methoxyflurane" le "Halothane".

"Methylphenidate" khothalletsa thibelo ea metabolism le primidone eketsa ea mahloriso tsa lona maling.

"Leucovorin" tekanyetso kgolo ho fokotsa liphello tsa primidone anticonvulsant. E tšoanang e sebetsa ho lithethefatsi "phenylbutazone".

likhothaletso itseng

Lithethefatsi "primidone" li ka sebelisoa ka ho rarahaneng kalafo anticonvulsant. Khanselwa le Phetolo ya lithethefatsi e ne e le butle-butle.

Ka hloko haholo, o ile a khethoa ho batho ba hōlileng le ba immunocompromised. Le ntshetsopele ya megaloblastic khaello ea mali moriana o hlakola behe kalafo le vithamine B12 kapa folic acid.

Ka taba moemeli fokotsa psychomotor liphetoho batho. Ka hona, ha ho ho laela ea bakhanni ba likoloi le batho bao mosebetsi oa e amanang le mechine kotsi.

Le tlhokomelo ea lithethefatsi ena e sebelisoa ka bana.

ho bolela ka tsela e tšoanang

Lithethefatsi ka nkeloa sebaka ke "primidone"? Analogues oa sesebelisoa sena ka rekoa ka famasi kapa odara ka World Wide Web.

Ho ea ka litsebi, ba le thepa tšoanang meriana tse kang "hexamidine", "Benzonal" le "Phenobarbital".

Testimonials

Bareki ba nka antiepileptic lithethefatsi tse kang "primidone" mo tlohela poeletsotlaleho feela e nepahetseng. Ho ea ka litlaleho tsa bona, lithethefatsi tsoeroe ke lefu la hantle le mosebetsi oa eona. Ho thibela ketsahalo ea sethoathoa a leeme le generalized. Hape, meriana ena e thusa ho fokotsa matšoao a lefu la sethoathoa.

Ha e le ba ulasan pelanggan mpe, hoo e ka bang kaofela ha bona e supa 'nete ea hore bukana ena e thusa ho hlaha ha palo e khōlō ea litla-morao. Ka hona, ho sebelisa pheko joalo lokela ho feela ba ho ngaka a khethoe.