Mafu a lefa - batho liphetoho liphatseng tsa lefutso phatsa ea lefutso

mafu a lefa na le ntlha e etiological ka mokgwa wa liphetoho liphatseng tsa lefutso, tseo e seng feela sesosa sa bopengwi, empa hape ama pathogenesis bona. Maemong ana ho na le predisposition liphatsa tsa lefutso.

liphetoho liphatseng tsa lefutso lefa di arotsoe ka liphatsa tsa lefutso le mafu chromosomal. Pele ho fetile ntle liphetoho leha e le life tse fetang melokong e, e leng e etsa hore ke nke khato ka la phatsa ea lefutso mutated, empa pathogenesis lona e amanang le lihlahisoa e ka sehloohong ea liphatsa tsa lefutso (e sa tloaelehang sebopeho, ho haella ha enzyme kapa protheine).

Chromosomal lefa lefu classified ke mofuta oa syndromes phetoho liphatseng tsa lefutso tse bakileng dipalo tsena (aneuploidy, polyploidy) le mehaho (duplications, translocations, inversions, deletions) rearrangements. Ho na le boetse ho na le makala a mafu mono- le polygenic. Ea bobeli, hangata ka lebaka la ho predisposition lefa.

sehlopha se seng ke bopengwi a hlahang nakong fetal le lumellane ho ba lisireletsi mè. Mohlala ke lefu lena haemolytic ea sa tsoa tsoaloa le.

mafu a lefa la monna ba haholo-holo tse amanang le boemo ba batsoali ba ka lehlakoreng la 'mè. Ka mohlala, haeba 'mè' nileng ba ba le kankere ea matsoele, ho na le kgonego phahameng a thulana le bothata bo tšoanang. 'Me haeba ho na le mong ka rōna haufi le phumano lefu kgonego e imena habeli. Haeba motho a e kotsing e kgothaletswa ho etsa mammogram selemo le selemo. Ho lumeloa hore kankere ea matsoele e bakoa ke liphatsa tsa lefutso mutated ba a tšoaetsanoang ka ho tswa ho 'mè kapa ntate. Ha liphatsa tsa lefutso li sebetsang ka tsela e tloaelehileng, lisele tsa litsoelesa le mammary hlahisa hantle, ka ketsahalo ea ditlolo ka qala kankere ea matsoele.

Ha e le 'mè ea lulang botsofali bo qhetsola lesapo le ho oa ha tse nyenyane kapa ba e khutsoanyane, joale osteoporosis. bana ba hae e hlaha kotsing e khōlō ea lefu e tšoanang. Joalo mafu a lefa ke lintho tse tloaelehileng haholo ka malapa. Ho motho ea ka ke ke susumetsa liphatsa tsa lefutso tsa bona le ho felisa e sa tšoaneng le lintho tse kotsi (age, bong). Leha ho le joalo, kamoo ho ka ho boloka bophelo bo botle ba lesapo le ho fokotsa likotsi tse teng. Ho etsa sena, o lokela ho latela lijo tse ruileng vithamine D le k'halsiamo, kopanela ikoetlisa, felisa ho tsuba le ho ho noa joala.

lefu la pelo e nkoa e le bogolosegolo motona. Leha ho le joalo, ba ile ba ba le sesosa e ka sehloohong ea ho shoa ha 'mè le na le lefa. Phahameng khatello ea mali (kgatelelo ya madi), k'holeseterole e, 'me lefu la tsoekere ke kotsi lintlha sehlooho tseo fella ka ho ntshetsa pele lefu la pelo' me a ba le predisposition liphatsa tsa lefutso. Fokotsa kgonego ya ho kula ka khomarela bophelo le bophelo bo botle le ho laola liphello tsa ho imeloa kelellong. Ho fumana lefu le tlas'a taolo, o lokela ho ea bakeng sa kamehla cheke-baholo.

Ho tepella maikutlong hape oela dihlopha tsa mafu a lefa batho. ntshetsopeleng lona ama liphatsa tsa lefutso, hormonal sebopeho, k'hemik'hale boko imbalance, ho ba teng ha liketsahalo sithabetsang. Haeba batsoali ba sa le bothata ba ho lefu lena, bana le bona ba na le tšekamelo ea tšoanang. Haeba ho na le histori ea lelapa ea lefu lena le lokela ho latela liphetoho tsa feto-fetoha, ho rarolla bothata bona hoseng 'me a nka kalafo hae.

Autoimmune mafu lefa haholo-holo ama basali feela 'me o fetela fatše ho' mè oa ho morali. Haeba motsoali a utloa bohloko ho tswa ho e ruruhisang ramatiki, insulin e itšetlehileng ka lefu la tsoekere kapa lefu le leng autoimmune, ho na le ke e phahameng monyetla wa phetiso lona ho moloko o latelang. mafu tsena li se hakaalo hore e tse amanang le lefu le tšoanang. Ka mohlala, e mong ka lapeng hore develops lefu celiac, 'me e mong - multiple sclerosis.