Lithethefatsi "Prosulpin": pukwanana amohele taeo, ulasan pelanggan le analogues

Medicine "litaelo Prosulpin 'bakeng sa tšebeliso e hantle e le e matla ea lithethefatsi antipsychotic hore e sebediswa ea ho phekola ba mafu a tse fapa-fapaneng tsa tsamaiso ea methapo le maloetse a mang. Lintlha tse ling mabapi le ho lokisetsa ka holimo, bala on.

Tlhaloso Short ya ba lokisetsa ho ea

lithethefatsi ena ke ea sehlopha sa ka go engwa legatong -benzenamine. Ka tsela e 'ngoe, re ka bolela hore ke e tloaelehileng ea antipsychotic lithethefatsi "Prosulpin". litsebi Guest supa hore bohato lona o ikemiseditse ho thibela dopamine receptors (D2i d3 lego). Ka lebaka la ho boletsoeng ka holimo antipsychotic lithethefatsi hlahisa le phello e phekola.

50 kapa 200 mg, ea letlapa le leng e na le sulpiride "Prosulpin" lokisetsa.

litla-morao ha etellang lithethefatsi, ya e le hantle, etsahala maemong a mang. Ka lebaka leo, ka mamello nakong eo tsela ea phekolo ka holimo antipsychotic lokela ho ba tlas'a tlhokomelo ea ka thata-thata ea meriana.

moriana ena e na le liforomo tse 'maloa. Ho fumaneha ka foromo Letlapa le ka mokgwa wa capsules, tharollo bakeng sa tsamaiso intramuscular le sephalli bakeng-ja.

Lithethefatsi lokela ho bolokoa ka tsela e tloaelehileng wa kamore, empa se phahame ho feta 25 likhato Celsius. sebaka lokela ho hantle a sireletsa ho tloha leseli le mongobo. Hoo e ka bang lilemo tse peli ya raka, athe bophelo "Prosulpin" lithethefatsi. Analogues ho ke ke ha ho le thata ho fumana. Meriana tse rekisoang e mengata e fapaneng baemeli bakeng sa lithethefatsi tse boletsoeng ka holimo.

The bohato diokobatsi ba boletsoeng ka holimo phekolo moemeli

Medicine "Prosulpin" eo Foto fanoe ka tlase, ke moemeli antipsychotic hore ke neuroleptic. sulpiride ntho e loketseng ho thibela ya receptors dopamine sebakeng tuberoinfudibulyarnoy khothalletsa keketseho ea bohlokoa ho maemo prolactin. Re lokela ho hlokomela hore ka mefuta e fapaneng lengolo la 60-80% fapana thibela dopamine receptors.

Ea bobeli e fapana ho lekaneng phahameng tšoana ho benzamide, e leng tšobotsi ea tšobotsi e kang e le hantle bifazicheskoe ka tsamaiso neurotransmitter dopamine. Ho phaella moo, ba thibela keketseho ea ho synaptic dopamine tswakana sebakeng, i.e. antagonize presynaptic likoloi receptor D2 d3 lego.

Re lokela ho hlokomela hore paakanyong holimo ke tekano neuroleptic mosebetsi. bobeli e ho kopantswe le timoanalepticheskim mong le Stimulating bohato oa sesebelisoa sa.

Lithethefatsi ka holimo o na le tsena tse latelang litla diokobatsi:

• antiemetics (dopamine receptor thibela likepe o etsoa thunye hlatsa libaka setsi);
• antidepressant;
• antipsychotic.

Sulpiride bontša litla antidepressant ka tekanyetso ho fihlela ho 600 mg,. Holimo tokisetso ena e se e ile a re litla antipsychotic ea lithethefatsi ena ka 'mele.

Ho phaella moo, lithethefatsi "Prosulpin" thuto e bontša se hlahisa le phello e khetha ka hypothalamus le, matšoao a seso gastric le gastroduodenitis. Ka tsela eo hatella litsi phahameng nyakallo tsa tsamaiso ea methapo le kutloelo-bohloko, ho ntlafatsa phepelo ea mali ho mala, potlakisa keketseho ea granulation dinama tse nyenyane tse, le thulaganyo ya mucus secretion ka mpeng, ho thehoa nkeloa sebaka epithelium, keketseho ea methapong ntlafatsa dinama tse nyenyane tse.

Ke mang ea lokelang ho e nka pheko ee?

ke eng lithethefatsi "Prosulpin" bontšang bakeng sa ho sebelisoa? Bakeng sa merero ea phekolo, le lithethefatsi ka holimo li sebelisoa mafu joalo:

• mafu psychosomatic;
• khatello ea kelello liso tsa pampitšana eo tshilong ya dijo;
• liso tsa ka maleng bontshang matshwao;
• gastroduodenitis;
• mala seso;
• ho teneha feela mantle a (mala);
• liso tsa ka maleng medicated;
• nonspecific ulcerative colitis;
• Ho tepella maikutlo fapaneng etymology;
• neuroses;
• arabelang ho tepella maikutlo;
• dysphoric boloetse;
• bokuli ba ho kopana hlooho;
• foleng maloetse a kelello ;
• migraine;
• mafu a mafu a kelello a hlobaetsang;
• molikoalikoane etymology fapaneng (skeletal neuritis, vertebrobasilar insufficiency, basilar, lefu Meniere e, nattokinase mecha ea phatlalatso).

Lithethefatsi "Prosulpin" litaelo bakeng sa ho sebelisoa e fana ka ho etsa kopo bakeng sa kalafo ya mafu a boitshwaro le psychoses bakuli ba banyenyane, bana ke hore. Ena le mafu a kang ho intsa kotsi, pherekano, stereotypes. Hape moriana "Prosulpin" litaelo bakeng sa ho sebelisoa tsitlella eletsa ho sebelisa e le karolo ea tsela ea phekolo ea autism bana ba sa feptjoeng. sesebelisoa sena e sebediswa ea ho phekola bakuli ba mocha ea lilemo li lilemo tse 6.

Contraindications ho tšebeliso ea lithethefatsi e boletsoeng ka holimo

Lithethefatsi "litaelo Prosulpin 'bakeng sa tšebeliso buelloa ha ha mokuli na matšoao a mafu a tse latelang:

• hypersensitivity ho moriana;
• hyperprolactinemia;
• prolaktinzavisimye lihlahala (kankere ea matsoele, pituitary prolactinoma);
• mafu a feto-fetoha;
• dino chefo a hlobaetsang le hore na lino tse tahang;
• boitšoaro bo mabifi;
• pheochromocytoma;
• Hlobaetsang chefo ke lithethefatsi kapa lithethefatsi robetse lipilisi;
• ferekane kelellong psychosis.

e re tsena tsohle li contraindications ka tieo. Hape moriana "Prosulpin" litaelo bakeng sa ho sebelisoa a hanela ho fa basali ba letsoele-fepa lesea la bona, bana ba ka tlaase ho lilemo tse 18 (bakeng sa 200 mg, lipilisi), bakuli ba mocha ho fihlela ho lilemo tse 6 (50 mg, lipilisi).

Ho phaella moo, e lokela ho a hopola, e boetse ke sa rateheng ho sebelisa lithethefatsi "Prosulpin" congenital khaello ea lactose, tsoekere-galactose malabsorption, lactose se mamellane. Contraindications ho tshebediso ya mahlahana holimo phekolo ea sebetsa le ho basali ba baimana. Sebelisa bakeng sa bakuli ba joalo lumelloa feela ha melemo lebeletsoe ea lithethefatsi e tla ba e phahameng haholo ho feta kotsi le monyetla oa ho lesea le eena.

litla-morao

Ha fumana "Prosulpin" ho lokisetsa (pukwanana bontša ena), o ka ba le liphello tse ling lehlakoreng:

• ka lehlakoreng la tsamaiso ea endocrine - galactorrhea, dysmenorrhea, amenorrhea, frigidity, ho hloka matla;
• ho tloha methapo ea kutlo - robatseng, ha thothomela hohle, molikoalikoane, ho dyskinesia pele, lefu extrapyramidal, somnolence, akinesia le mesifa hypertonicity, akathisia, dilenaneo nyakallo;
• eketseha ka mosebetsi oa enzyme (ho tloha tshilo ya dijo le);
• haemolytic khaello ea mali, leukocytosis, aplastic khaello ea mali, granulocytosis, purpura, thrombocytopenic etsahala tekanyetso e phahameng "Prosulpin" ho lokisetsa (by ketso mali le lisele tsa mmele litsamaiso);
• tachycardia, orthostatic hypotension, fokotseha kapa eketsehileng khatello ea mali, ho lelefatsa le karohano QT, maemong a mang ntshetsopele ya mafu a kotsi tse kang torsade des ka pointes lefu (ea pelo le tsamaiso ea lona).

Hape bakela litla tse ling lehlakoreng lithethefatsi ena. Lithethefatsi "Prosulpin" (taeo e arabele lingaka le bakuli likarabo ho paka ena) ka qholotsa liketsahalo joalo e sa thabiseng e le dyskinesia tardive, e tšoauoa ka mekhatlo involuntary morethetho tsa sefahleho kapa puo ea (le e nako e telele ho phekola thupellong neuroleptics lihlopha tsohle), hyperthermia. Litsebi li lemosa hore le tabeng ea ho qetela ke ea bohlokoa haholo-holo ka nako ea ho hlakola mokhoa holimo, kaha ho phahama mocheso ka 'na ba e bontsha gore go ya mafu a joalo kotsi tse kang lefu neuroleptic bolaeang.

phaello ea boima ba 'mele, e ile ea eketseha ho fufuleloa, letlalo lekhopho le ho hlohlona - kaofela ha liphello tsena lehlakoreng le ka boela etsa hore lithethefatsi "Prosulpin". Litaelo, maikutlo ho tswa ho litsebi li nkhothaletsa ntlo maemong a joalo ho thibela ho nka meriana ka holimo 'me ba batla hang-hang ngaka thuso le likeletso.

Sebelisa nakong ea bokhachane ka holimo ho moemeli phekolo

Teratogenicity ya moriana ha e so fumane ka lebaka la liteko liphoofolo. Basali ba bang ba ba ileng ba sebelisoa moriana nakong ea bokhachane hao, 'me ha aa ka a boloka e le hantle tse boletsoeng ka holimo. Empa bakuli bana o ile a fumana e tlase-lethal dose ka tieo le bolela "Prosulpin". Litaelo tsa tšebeliso, litsebi li ea sebele ha ba na lintlha tse hlakileng mabapi le ho sebelisa chelete e le e phahameng ea boleng bo sa kang sulpiride. Ho na le boetse ho na le ha ho na ya data ka phello ea ho paakanyong boletsoeng ka holimo bakeng sa tsoelo-pele ea boko ba fetal.

E le precaution ho litsebi ha ho eletsa ho sebelisa meriana ena bakeng sa basali ka mmuso. Leha maemong a mang, a ntse a lumelloa ho phekola ba lokisetsa ho tse boletsoeng ka holimo ea bakuli, ba lebella hore ngoana, empa ka tieo ka tekanyetso fokolang haholo.

Litsebi hlokomela hore haeba 'mè e fumana neuroleptics phekolo nako e telele nako, le makumane a sa tsoa tsoaloa ba le mathata a le tshilong ya dijo pampitšana mosebetsi (mohlala, bloating).

Ha mosali e mong o sebelisa lithethefatsi nakong ea pele ho fana ka puo, ho laola 'mele oa hae' me tsoelo-pele ea lesea ka ngaka e tlamang.

E lokela ho a hopola hore e ntse e feta ka lebese lithethefatsi "Prosulpin". Litaelo tsa tšebeliso, litsebi li ea sebele ha ho kgothaletsa ho e hapa, ka nako diabolololo.

Tsela ea ho nka lithethefatsi "Prosulpin"?

Tataiso e fana bakuli sebelisa holimo antipsychotic mong le e mong lihora tse 8 ho pilisi e le 'ngoe. E sa kgothaletswa ho nka moriana mora 16.00, ka mosebetsi oa eona o haholo eketsa ka nako ena. Re lokela ho hlokomela hore e sebediswa ho sa tsotellehe hore lijo le hlatsoa fatše le chelete e lekaneng ea ho ba lokisetsa ho mokelikeli "Prosulpin".

Tablets hore na 200 mg, ea sulpiride, ba ile ba amohela ka matšoao a hlobaetsang ea bokuli ba ho kopana hlooho, delirious psychosis le ho tepella maikutlo. moriana ka nkoa ka tekanyetso aroloa. letsatsi lebetsoeng le lona lethal dose ke 100 mg,, kapa ka 5 lipilisi.

Tablets, tse akarelletsang 50 mg, ea sulpiride, e fana ka thupelo ea ho nka, haeba mokuli o matšoao a neurosis, ho tšoenyeha. Ka libeke tse 4, bakuli bana ba lokela ho ja bonyane ba e mong le e lebetsoeng le matlapa 3 ka letsatsi.

Hape, lipilisi tsena ka nkoa bakeng sa bana ba nang le mathata a tebileng boitshwaro. A le lilemo li bakuli joalo lokela ho lula ba le lilemo li phahame ho feta 6. The lebetsoeng le letsatsi lethal dose bakeng sa bakuli sehlopha sena se tsoa 5 ho tse 10 mg, ka ho ya ka 10 lik'hilograma boima ba 'mele.

overdose

Manual e bontša hore overdose sulpiride lesedi e lekanyelitsoe. le matšoao tse latelang ka 'na ho ketekoa ka boemo ena ka mamello:

• puo ea protrusion;
• dyskinesia le torticollis spasmodic;
• thothofatsang Pono;
• ommeng molomo;
• khoneha ntshetsopeleng ya NSAs;
• matšoao a extrapyramidal;
• e ile ea eketseha ho fufuleloa;
• ho nyekoa ke pelo;
• robatseng;
• gynecomastia;
• lefu Parkinson;
• eketseha ka khatello ea mali.

Kalafo ea boemo ka holimo tsa ba le mamello e etsoa ka tsela e latelang:

• a hlatsoa mala oa mamello;
• ea khethiloeng ke carbon butswe;
• le phekolo e hlophisitsoeng.

Haeba ho hlokahala, maemong a matla, ngaka e ka 'na tsa fana ka mellwane eketsehileng, tse kang ditharollo diuresis Infusion mesebetsi a alkali kapa tlhokomelo ea bohlokoa' meleng.

Re lokela ho hlokomela hore ho lokisetsa ena e nkiloeng karolo e 'ngoe ka hemodialysis.

dihlopha tse itseng tsa bakuli ba lokela ho nka mehato e khethehileng ha u sebelisa "Prosulpin" lithethefatsi. Hona ho sebetsa haholo-holo ho basali ba nang le nako kamehla, bakuli ba hypotension matla le kgatelelo ya madi.

Ho boetse ke habohlokoa ho bakuli ba lefu la sethoathoa selelekela electrophysiological le tlhahlobo ea tleleniki. E lokela ho a hopola hore lithethefatsi "Prosulpin" lowers monyako bakeng sa mosebetsi inkela ka mahahapa.

Ho feta moo, ha ea khannang lipalangoang hloka tlhokomelo e khethehileng nakong ea kalafo le lithethefatsi tse ka holimo. Ho boetse ke habohlokoa ho fokotsa mesebetsi e hlokang liphetoho potlako psychomotor le phahameng mahloriso.

Sebelisana le mahlahana a mang phekolo

Litaelo ha tieo khothalletsa hore e boletsoeng ka holimo ea lithethefatsi ka ho kopantswe phekolo le levodopa. The dintho tse peli a sebetsang a ke khahlanong le lōna. Haeba le mamello, ebile ba le bothata ba ho lefu Parkinson, o levodopa, ngaka e le moemeli tlameha ho khetha hore na le fokolang haholo litla extrapyramidal.

Arrhythmias kang torsades de Khao pointes a ka bakoa ke motswako "Prosulpin" lithethefatsi le:

• lithethefatsi antiarrhythmic, eo e leng ba sehlopha sa IA (lithethefatsi "Dizopiramid" "quinidine");
• lithethefatsi "pimozide," "Haloperidol", "thioridazine" "Cisapride", "Pentamidine" imipraminovymi antidepressants;
• lithethefatsi antiarrhythmic tse kenyelelitsoe sehlopha sa boraro (le bolelang "Sotalol", "Kakamiodaron");
• meriana tse bakang matšoao a mafu a tse kang bradycardia (beta-blockers, k'halsiamo le kanaleng blockers);
• lithethefatsi e tlatsetsang ho ponahalo ea lipontšo tsa hypokalemia (laxatives tse stimulatory, hypokalemic diuretics, tetracosactide, glucocorticoids);
• dopamine ba khahlanong le lōna (antiparkinson): "apomorphine", "Amantadine" "Lisuride", "Ropinirole", "Entacapone" "Bromocriptine", "selegiline" "Pramipexole" "Piribedil");
• antipsychotic lithethefatsi hore na matla a ho etsa hore matšoao a torsades de Khao pointes ( "Chlorpromazine" "Amisulpride," "Tsiamemazin" "pimozide," "Droperidol" "levomepromazina" "tiapride," "Sertindole" "Veraliprid" "Sulpiride") ;
• lithethefatsi tse nang lithium (e qetellang haholo ho eketsa kotsi ea maloetse extrapyramidal).

Hape, haeba leha e le efe, le lithethefatsi "Prosulpin" ha ea lokela ho sebelisoa ka kopanelo le joala. Last potentiates phello sedative tsa neuroleptics.

Ho phaella moo, haeba re nka ho tse boletsoeng ka holimo ea lithethefatsi hammoho le centrally Stimulating dintho (-ba khahlanong le asthmatics, anorectics), mokuli a ka ba le matšoao a nyakallo matla, ho tšoha, ho tšoenyeha, e ngongorehisa.

E lokela ho a hopola hore e meriana antipsychotic lowers boemo ba katleho ya ropinirole.

Baemeli "Prosulpin" moemeli phekolo

Analogs tsa antipsychotic tse ka holimo:

• "Betamak T100";
• "Vero Sulpiride";
• "Betamax T50";
• "Depral";
• "Betamax";
• "The thuto ya";
• "Betamax T200";
• "Sulpiride";
• "Eglonil";
• "Sulpiril";
• "Eglek".

Empa fetohile ntle rerisana pele le ngaka ha e khothalletsa "Prosulpin" taeo pukwanana. analogues lona le bona ba na litla bona motho lehlakoreng. Ba ile ba ka tlisa kotsi e khōlō ho bophelo bo botle oa mokuli.

The likarabo ea mokhoa oa tsa bongaka "Prosulpin"

Reviews of moriana holimo hangata khothatsang. A ngata tsa bakuli ho e hapa, ka re tepelletsang. Ba ba bolela hore sesebelisoa sena se ba thusa ho felisa matšoao a lefu lena ke hoo e ka bang 100%.

Ho feta moo, ba bangata ba bakuli lekaneng likarabo, e leng ho ka mafu a kang bokuli ba ho kopana hlooho, enterocolitis, colitis, psychosis, enteritis, lefu ulcerative, ho teneha feela mantle a syndrome,, o ile a nka lithethefatsi "Prosulpin". Reviews of bontša hore maemong 'ohle, ke sesebelisoa sa hlahisa e hlollang ke pholiso e le hantle. Ho phaella moo, bakuli ba tlaleha hore litla-morao li etsahala seoelo haholo.

Lithethefatsi ka holimo o na le litla bo tebileng boo lehlakoreng, kahoo sebelisa ntle ho rerisana pele le ngaka e tieo thibetsoe.