Lefu Addison ke mang?

lefu Addison o etsahala ha le sebetse hantle ya cortex adrenal. lefu lena e fumanoa ka banna hammoho le basali, haholo-holo bohareng-hōlileng (lilemo tse 30 ho isa ho 40). Ke lefu le sa tloaelehang, leo e ngolisitsoeng ka motho a le mong ka 100 tse sekete. Population. lefu Addison Biermer ka ntshetsa pele ka lebaka la ho dithulaganyo autoimmune, mafu a tšoaetsanoang (mokaola, lefuba le adrenals feberu ea mala), 'me ka amyloidosis le lihlahala tse kotsi. Ka 70% ea bakuli, lefu lena le hlaha ka lebaka la ho hlōleha ka boitshireletso ba mmele (lisireletsi ba qala ho nka lisele tsa 'mele bakeng sa' mele e 'ngoe, ba hlasela le ho felisa bona). Le ho timetsoa ha lisele adrenal cortex decreases tswakana gluco le mineralocorticoids (cortisol, 11-deoxycorticosterone, aldosterone). Bo-rasaense ba 'nile ba bontša hore glucocorticoids laola sa tšoaneng dithulaganyo skeletal' meleng (o laola khatello ea mali, ka insulin mahloriso, ho akarelletsa le molao oa tsamaiso ea protheine tswakana, lipids le lik'habohaedreite).

Gipokortitsizm hangata e hlokomela bakuli tšoaroa le li-hormone tsa cortex adrenal. Maemong a mangata, ho etiology ya lefu lena le ntse o hlola ka ho e sa tsejoeng. Adrenal insufficiency classified ka mathomo le se mahareng. hloleha mathomo develops ka hlōloa ha dinama tse nyenyane tse adrenal, 'me ea bobeli - ka lebaka la ho haella tlhotlheletso ya hormona adrenocorticotropic.

Addison oa Mafu Matšoao

matšoao Clinical tsa lefu le bakoang ke khaello ka phelang matsoai e le glucocorticoids. Likarolo tse ngata e khethollang ke bofokoli, hypotension, dysfunctional gastrointestinal (ho nyekoa ke pelo, ho lahleheloa ke takatso ea lijo, ho hlatsa, pipitlelano, letšollo tseo hangata li nkeloa sebaka). Ba bang ba bakuli hypochlorhydria.

lefu Addison e e tsamaea le eketseha teneha kapa maikutlong tepeletseng maikutlo, ho tšoaroa ke hlooho khafetsa 'me lefu la ho hlobaela. X-ray ea sefubeng sa bontša ea fokotseha ka boholo ba pelo. The electrocardiogram tlaleha ka lipontšo tsa hyperkalemia (phahameng mahloriso potassium maling). Letlalo pigmentation ha bonahatsa ho tiea ha lefu lena, leha ho le joalo, keketseho e kapa fokotseha ka ho phekola ka bopaki ka ho atleha ha ho bohato phekolo.

lefu Addison e tšoauoa ka tšimoloho ea matšoao a mahareng ka tlase e matla. Haholo ka seoelo le lefu lena o bontša ka boeona e ntle pigmentation (jwalo e le sehlooho sa "tšoeu Addison"). Sesosa se ka sehloohong sa lefu lena ke lefuba adrenals. A ho ba sieo tsa kalafo loketseng ho tse lefu Addison e rarahaneng. matšoao Clinical ba Amplified: ho nyekeloa ke pelo, ho hlatsa, letshollo, khatello ea mali marotholi sharply, eketsa ea mahloriso ea potassium maling. Ka mali pheriferale ya naetrojene barrel eketsa palo ea lisele tse khubelu tsa mali, hemoglobin. Ka hona, haeba nakong ea bothata addisonicheskogo mamello ha e fana ka thuso e nakong, a ka shoa ka lipontšo tsa renal le lefu la pelo.

The entsprechen bohlokoa ka ho fetisisa le laboratori eo ho fumanoe ke diteng tsa 17-OCS ka lero la mali le 17-KS ka moroto le, hammoho le ea fokotseha ka maemo tsoekere mali. Morphological hlahloba mali a bontša lymphocytosis, eosinophilia le ESR lieha.

lefu Addison e le farologantswng la ho tswa le mafu tse latelang: lefu la tsoekere boronse, pellagra, chefo arsenite le Bismut Argentum. Lefu lena le hangata e na le ka tsela e sa foleng le peaking nako le nako. lefu Addison Biermer tiea laolwang ke pontšo ea lipontšo tse khōlō tsa lefu lena le, hammoho le lenane la lithethefatsi tse hlokahalang ho lefella bakeng sa insufficiency adrenal.