Hormone phekolo:-motheo ea eona le ho pharalla ha kopo

Hormone phekolo ke mokhoa oa phekolo oa pathologies tse sa tšoaneng, joalokaha e-hormone - ke metsoako protheine e khona ho sebetsa ka mekgwa e fapaneng pathogenetic hore ntshetsa pele ka 'mele oa motho.

Hormone phekolo e atisa ho sebediswa ea ho phekola ba li-hormone ea HIV letsoele lihlahala. phekolo ena o boetse o bitsoa-ba khahlanong le estrogen bananeng, ka o ile a laela ka ho thibela liphello tse mpe tsa estrogen bananeng, ka lisele tsa sebopeho hlahala.

Tsa lithethefatsi tse hangata ka ho fetisisa tseo ke li behetsoeng kankere ea matsoele, e se eka ho builoeng lithethefatsi "tamoxifen", hammoho le inhibitors aromatase.

Ke habohlokoa ho hlokomela hore phekolo hormonal e tšoauoa ka systemic kgahlamelo ya maqhubu a ho 'mele, kahoo ho ka sebelisoa ho timetsa lisele tse bakeng sa kankere ka mor'a mahlaseli phekolo kapa ho buuoa e le hammoho le ka mor'a a e-ja tsa phekolo ea lik'hemik'hale ho fokotsa menyetla ea boipheto lefu lena.

Bontšang bakeng sa kalafo ya li-hormone e:

• kotsi e phahameng ea ho ba le kankere ea matsoele;
• khutlela ho le kankere ea matsoele noninvasive;
• itaolang kankere, ha e ke ho hlokahala hore ho fokotsa hlahala boholo bakeng sa mekhoa e meng kalafo;
• metastatic hlahala.

phekolo hormonal bakeng pathologies tsena e lebisitsoe ho thibela kapa ho timetsa receptors tse nahanela estrogen bananeng, hammoho le ho fokotsa ea mahloriso ea li-hormone ena maling.

Ho tloaelehile haholo le li-hormone Phetolo phekolo bakeng sa basali, e leng o etsoang ho felisa maloetse menopausal. phekolo ena ke feletseng fapaneng ho tswa tekanyetso kalafo hormone, ha e ntse e tsoela ho phethoa khaello bona 'meleng, ho ena le ho thibelo bona.

Mogodisa Phetolo phekolo e fumana analogues fapaneng hormone ho kopanela liphate, e leng ka tsela e atlehang felisa liponahatso tse joalo tsa insufficiency tsa tshebetsong popelo ke litlhaselo mocheso le ho fufuleloa ka tsela e feteletseng, ho tšoaroa ke hlooho, teneha kapele le kholofalo memori kapa ka lebaka la ho haella estrogen bananeng mahloriso.

Seo ho Noa ka menopause, ngaka e lokela ho laola. Maemong a mangata, ho laela le lethal dose tlaase-tlaase tsa estrogen bananeng, ho kopantswe le progestogen, e thibela ntshetsopele ya dithulaganyo hyperplastic ka endometrium ena. Ka ho etsa joalo, phekolo hormona se lokela ho etsoa bonyane lilemo tse 5-7, e leng se etsang hore ho be bonolo ho thibela ntshetsopele ya osteoporosis le myocardial infarction har'a basali poso-menopausal.

Ke lokela ho bolela hore li-hormone kalafo o etsoang tsoa e seng feela har'a basali empa hape har'a banna ba neng ba khetholla ea tšoelesa ea senya ke kankere. Tabeng ena, e-ba khahlanong le androgen phekolo, e thusang thibela keketseho, keketseho le ntshetsopele ya lisele tse kankere.

Ka ho phekola androgen thibela likepe a sebelisa, tse tšoaroang ke faola tsa bongaka kapa ke abela antiandrogens. Estrogens ba atisa ho sebelisoa, e leng thibela metsoako ea secretion ea LHRH thibela metsoako ea ka tšebetso ea lisele Leydig le lisele tse cytotoxic tsa adenocarcinomas tsa tšoelesa ea senya tšoelesa.