Lithethefatsi "Colchicine". Litaelo tsa tšebeliso

Lithethefatsi "Colchicine" ke sehlopha sa alkaloids le limela tse ling-nkiloeng mahlahana cytotoxic. Lithethefatsi o protivopodagricakih, phello analgesic. Antimitotic moemeli e na le phello e inhibiting ea lisele tsa mmele le leykopoez fokotsa lahla nefagotsitiruyuschimi tsoekere le leukocytes phagocytic, thibela sebopeho sa fibrils amyloid. Meriana thusa hore ho ho tlōla phetiso neuromuscular, susumelletsa ka gastrointestinal pampitšana mosebetsi. Ho bolela le phello e tepeletsang maikutlo ka ho hema bohareng le eketseha, khatello constricts methapo ea mali, ho fokotsa mocheso. Ho noa ea tsamaiso tshilong ya dijo ka potlako. Lithethefatsi fetisa enterohepatic recirculation. Phahameng concentrations tsa lithethefatsi li fumanoa ka spleen, sebete le liphio. A khaotsa ho tsuba ha matlotlo ka liphio le bile.

"Colchicine" meriana. Litaelo ho sebelisoa. ya litatoli na

Ho bolela ho ba laela hore tlhaselo gouty, bakeng sa thibelo ea boipheto la litlhaselo hlobaetsang gouty tsa botho ba, haholo-holo lilemong tse pele a mabeli ka mor'a hore ho fumana meriana gipourikemicheskih. Ke matšoao a kenyeletsa systemic scleroderma, lefu Behcet e, amyloidosis, la lelapa Mediterranean feberu.

"Colchicine" moriana. Litaelo ho sebelisoa. setlamorao

Ka lebaka la baeti ba fihlelang ho ya moriana o ka 'na lokela ho ketekoa matšoao a dyspeptic. Ka ho khetheha, ho nyekoa ke pelo, letšollo, ho hlatsa, ho ipolaisa tlala. Ka tloaelo ho, matšoao ana a tloaelehileng bakeng sa boemo ka mor'a hore tekanyetso e phahameng. Liphello mpe kenyeletsa alopecia nakoana, maemo phahameng tsa gamma-glutamyl le alkaline phosphatase, e amanang le sebete ho hloleha, mafu a ea liphio. Lithethefatsi ka etsa hore myelosuppression (leucopenia, aplastic khaello ea mali, agranulocytosis, thrombocytopenia), myopathy, ho tepella maikutlo, reversible spermatoschesis. Nakong ea phekolo tšoauoa neuritis pheriferale, liphetoho letlalo alejiki, malabsorption lefu bonahatsa ka ho khetheha, ho hloka oa vithamine ea B12. Ha laolwa entoe, ho na le ea moo ho teneha.

"Colchicine" le bolela. Litaelo ho sebelisoa. Bakeng sa boitsebiso bo eketsehileng,

Lithethefatsi ke khona ho ntlafatsa ketso ea lithethefatsi sympathomimetic le deprimiruyuschie. Motheong oa kopo e ho na le ke ho tlōla absorbability oa vithamine ea B 12. Ha ho kopantswe le tumello le lithethefatsi tse ling NSAID, susumelletsang motho mielodepressiu eketsa monyetla oa thrombocytopenia le leukopenia. lithethefatsi Cytotoxic khona ho theola e le hantle protivopodagricakih (keketseho ea acid e uric).

Lithethefatsi "Colchicine". Litaelo ho sebelisoa. overdose

Ha chefo e tšoauoa ho nyekoa ke pelo meriana, bohloko ka molomo le mpeng, letšollo le matla, ho hlatsa, hemorrhagic gastroenteritis. Bakeng sa boemo ba ho overdose e tšoauoa ka sa hlohlona la letlalo, fokotseha myocardial contractility, dehydration le makala hypovolemic le hypotension, hematuria, tsitsipana, ho tepella maikutlo ho hema, a nyolohela shoele litho, oliguria. Mohlomong ketsahalo e senya hepatocellular, a hlobaetsang le renal ho hloleha phallo, infiltrates methapo. matsatsi a mahlano ka mora hore lithethefatsi chefo ka qala ka lesapo moko hatelloang ka thrombocytopenia, leukopenia. Kalafo ea bakuli overdosing etsoa hore litsi chefo taolo.

"Colchicine" le bolela. Litaelo. theko

Litsenyehelo tsa ho ba moriana - ho tloha ka 1450 li-ruble.