Fele - ke eng see? Features

E nako e telele e ne ba nahana hore tikoloho mala, batlang e le nyopa tikoloho e microflora. Ka mpeng, ka dikahare tsa sona tsa - acid e, kapa e le feela ba ne ba sa phela e le 'ngoe e phelang. Phumano ya Helicobacter pylori ka pampitšana ea gastrointestinal e tlisa phetoho e kholo khopolo ea sebopeho sa mafu gastrointestinal: gastritis, duodenitis, liso tsa ka maleng gastric le liso tsa ka maleng duodenal, kankere gastrointestinal le kalafo bona. A sehloohong sena a re hlahlobeng ka ho qaqileng seo a fele. Ke mokhoa itseng ea kalafo le fetohileng e ratoa haholo lilemong tsa morao tjena.

Excursion ka histori ea Helicobacter pylori

Ha e le hantle, le baktheria ho ile ha fumanoa e le nako e telele 'me ha' ngoe. Ka lekhetlo la pele hona ho etsahetse'ng qetellong ea ho qetela lekholong la lilemo la. E ne e le 1886. Jagiellonian University Professor V. Yavorsky lemoha libaktheria bath spiral sebopeho ka lintho tse bonahalang tse gastric. O ile a fa lebitso la baktheria Vibrio rugula, 'me a etsa tlhahiso ea hore ho phetha karolo ea ka ntshetsopele ya mafu gastric.

Leha ho le joalo, tlhokomelo e loketseng ha e bile Yavorsky mosebetsi sechabeng bongaka. Lilemo tse supileng hamorao, le rasaense ea Setaliana D. Bidzodzero ile microorganisms tse joalo tse tsoang pampitšana tshilong ya dijo ea ntja. Se latelang, ba ile a re ho ba teng ha libaktheria ka lisele tsa tsona li mala ho tloha bakuli sebetsa ulcerative ne Professor Morozov Moscow. E ne e se e ea qetellong ea 70s ea tse lekholo tse fetileng.

boiteko ba ka ho eketsehileng le ka tsela e itseng ka hlalosa, go arologana, hore e hōle ka laboratoring le hlahloba boleloa ka mabitso baktheria e se e etsoa ka 1979 le 1981 Maaustralia Marshall le Warren. 'Me ba atleha. Marshall ho ile ha tšoaroa boiphihlelo katleho intša tshwaetso ya Helicobacter pylori le pholiso ea helicobacter gastritis rekoa ke tsela ea kalafo ea libeke tse peli le "metronidazole" le matsoai bismuth.

Mokhoa ona e bopa motheo fele ea kajeno ea Helicobacter pylori. A bafuputsi ba sebete ka 2005 o ile a fumana Khau ea Nobel ka Medicine.

Lebitso la Helicobacter pylori phelang e ne e le ka 1989, hammoho le tlhaloso e feletseng le tlhophiso. Spiral baktheria phelang o khethile "heke" ea mala ( "pylori" - tswa Segerike "heke") infects libakeng tsohle tsa duodenum le mala. Ka karolo e khōlō ea gastritis, duodenitis, liso tsa ka maleng tsohle mala le liso tsa ka maleng duodenal fihlela bakeng sa kankere ea bona e molato ka kokoana-hloko ena.

Kotsi ea tšoaetso ea le Helicobacter pylori?

Helicobacter pylori, lula pampitšana gastrointestinal motho kapa phoofolo ho pores itshwara ka bang. Ka ho hloleha ho honyenyane ho boitshireletso ba mmele kapa ke phello e cumulative la khaello ea phepo, kapa mekhoa e kotsi butswe baktheria fetoha mabifi. e se kotsi? Phelang ka lera mucous tsa litho tsa ka hare - mala le duodenum - pathogenic kokoana-hloko ketso e ho eona.

Tshimolotse eketsehileng ho lokolloa oa liphiri, eo hampe ama dinama tse nyenyane tse gastrointestinal. Mucous bona e ba bo hlephileng, robeha, ho na le libakeng tse haholo ruruhileng le sebopeho sa liso tsa ka maleng. Foleng gastritis le bakoang ke pathogenic kokoana-hloko Helicobacter pylori sehlopha, ho fapana le tloaelehileng phetha molao gastritis, ha amenable ho phekola ka mekhoa e tloaelehileng.

Helicobacter pylori le kenella ka hare ho le dikarolo tsohle tebileng tsa dinama tse nyenyane tse, 'me kahoo sa angoe ke lithibela-mafu tse ngata (lithibela-mafu ha boa tsitsa ho acidity). Joalo vandalnye liketso tsa hae bakela dithulaganyo etsolloa ka mucosa le, ka mohlala, e le boemo ba precancerous, 'me, ka ho toba, ntshetsopele ya Oncology. Ho qoba sena, a sebetsa a fele tsa Helicobacter.

Phumano ya Helicobacter pylori ka pampitšana ea gastrointestinal

Ha mokuli oa tletleba ba ho nyekeloa ke pelo le ho indigestion, lesokolla, bohloko mathata a ka setulo, e leng boemong bo sa thabiseng bohloko sebakeng epigastric - pontšo e ka ho toba ho etswa diteko tsa ho ba teng ha phelang Helicobacter pylori. Tlhahlobo ea rente ke tsena:

• mali, tshekatsheka kakaretso ea antibody e, ho akarelletsa le ho ba teng ha H. pylori;
• setuloana and analysis bakeng sa ho ba teng ha libaktheria litšila;
• phefumoloho teko e thehiloe boikemisetso ba ho tsepamisa mohopolo ammonia ka pululo;
• cytologic hlahlojoe.

The mokhoa fetisisa o tšepahalang oa diagnosing tshwaetso ke dinama tse nyenyane tse biopsy tsa mucosa gastric le liso tsa ka maleng duodenal. Lesela e nkiloe hlahlojoe ke endoscopy.

ho bonahala a fele

Joalokaha ho se ho boletsoe ka holimo, e fele - e le tsela ea ho sebetsana le baktheria gastric.

Fele phethile kula ka pathologies joalo:

• matšoao a seso ka mpeng le duodenum;
• boemo poso resection (ho buuoa ho tlosa bakeng sa kankere);
• e re precancerous ka 'mele ea dinama tse nyenyane tse felloa ke matla;
• lymphoma.

Kotsing ke batho bao beng ka a utloa bohloko kankere. Recommended fele phekolo le ka bakuli ba gastroesophageal lefu reflux le tshebetso dyspepsia.

mekhoa fele

Fele - ke timetso, fele (English fele.). tekanyo ena, tse reretsoeng ho timetsa tshwaetso le Helicobacter pylori pampitšana gastrointestinal. mokhoa oa ho kalafo e bontšoa ka bakuli ba matla gastric seso kapa duodenal seso. mozindo lona itšetlehile ka nete hore ho noa meriana ka mohlala itseng.

Pele ho qala ya e le hantle e khannela thuto ka ho eketsehileng gastric mucosal dinama tse nyenyane tse ho ba teng ha lisele tse bolaeang.

Helicobacter pylori fele na le mefuta e 'maloa:

• mono,, moo ho hlokehang ka kalafo ea ho fumana mokhoa oa motho feela, hangata medicaments thehiloeng letsoai bismuth, kapa lithibela-mafu;
• Duo, phekolo kopanetsoe (vismutosoderzhaschee ntho mmoho lithibela-mafu);
• triplet, ka lebitso le bolela, kalafo ena le lithethefatsi tse tharo (bismuth, e lithibela-mafu le moemeli imidazole sehlopha);
• kvadriplet, theha a mane, moo ho triplet rarahaneng eketsa PPI phekolo (blockers ea acid e hydrochloric).

Mono-fele - ena e hoo e ka bang mohla o ile a sebelisa mokhoa kalafo ka lebaka la katleho ha eona (ka tlase 50%). O ne a le tloaeleha ka meso ba qalang le pele liteko helikobakterialnoy tsoara tshwaetso.

Fele sebelisa meriana e 'meli e na le bokgoni ba ho lahla helicobacter ka bang 60%,' me ho honyenyane haholo ka lintho tsa sebele kajeno ba tloaetse. sebelisoa kajeno fele ke eng? Phekolo regimens sebelisitsoeng ho eona.

Tripletoterapiya akarelletsa komponeng bismuth, e lithibela-mafu (amoxicillin le ka ho eketsehileng e sebediswa klaritomitsin) le imidazoles (ena fungicides).

Tsela ea lithethefatsi e mene - kaofela ha formulations ka holimo le le inhibitors proton e pompa (Sehlopha sena lithethefatsi antiulcer ikemiseditse ho fokotsa gastric acid e fana ka tlhahiso). Mekhoa ho bokgoni lona ke tshebetso indices 90% le 95% ho latellana. Mona ba bang ba a fele ka katleho Helicobacter e ka ba.

Meriana sebediswa bakeng sa fele

Hobane tikoloho ya asiti nullifies liphello tsa lithibela-mafu tse ngata, lethathamo la meriana ho felisa lekgutshwanyane haholo:

• lithibela-mafu;
• antiinfectives;
• vismutosoderzhaschie lithethefatsi;
• inhibitors proton e pompa;
• probiotics le prebiotics.

Lithibela-mafu li ka ho fetisisa e atisa ho sebelisoa ka phekolo fele

Kamoo ho qala a fele? Lithibela-mafu ke tse latelang:

• "Amoxicillin" kapa "Flemoksin Soljutab" - penicillin e sehlopha, e loketse bakeng sa bakuli ba ho fetisisa e sa kgothaletswa bakeng sa ho sebelisoa nakong ea bokhachane, renal ho hloleha.

• "Amoxiclav" - motswako wa amoxicillin le asiti kavulonovoy, e pharalletseng manyenyane lithibela-mafu khothalletsoang sebedisa hlokolosi ea eona liphio pathologies oa mokuli, nakong ea bokhachane lisosa lithibela-mafu dysbiosis matla.
• "Clarithromycin" kapa "Klatsid" - tlaase chefo lithibela-mafu erythromycin sehlopha boditsha ea ratoang ka ho fetisisa bakeng sa fele, ho e contraindicated ka masea ho fihlela ho likhoeli tse tšeletseng, basali ba baimana, sebelisoa ka hloko ka bakuli ba insufficiency renal kapa e amanang le sebete.
• "Azithromycin" - e seng ho fapana "Klaritomitsinu" le litla fokolang haholo lehlakoreng Leha ho le joalo, ho ke ke sa sebetsa khahlanong helicobacter pylori.

Lithibela-mafu "tetracycline" le "Levofloxacin" a sebelisoang ka tlaase ho moo, hangata e le maemong a tseo moo lithethefatsi tse boletsoeng ka holimo ha li na phello e batlang. Formulations tetracycline sehlopha bonahatse mabifi bohato ka ho ya ka lehlakoreng litla ka mor'a fele tsa Helicobacter hona ka seoelo e sebediswa.

lithethefatsi Antibacterial le-ba khahlanong le infective bakeng sa fele le

"Metronidazole" --ba khahlanong le infective chemotherapeutic moemeli nitromidazolovoy sehlopha, tse chefo haholo, tieo lumellane le joala le hanetsoeng nakong ea bokhachane.

"Makmiror" kapa "Nufuratel" - ya lithethefatsi antibacterial, le sebelisitsoe ka tabeng ea ho hlōleha ha "Metronidazole".

Vismutosoderzhaschie lithethefatsi

"De-Nol '- sena ke seo moriana o bontšitse tekanyo phahameng ka ho fetisisa ya neutralizing pepesehela Helicobacter. "De-Nol 'qhalana le kena bile slime ka le dikarolo tebileng ka ho fetisisa tsa lekala anngoeng ke likoluoa. litla mpe lehlakoreng na hoo e ka bang ha ho na, hammoho le contraindications (ntle le, ka tloaelo, ho ima).

Tlase atisa ho sebelisoa ho phekola Helicobacter letsoai metsoako bismuth:

• bismuth subsalicylate;
• bismuth subnitrate.

Litokisetso thehiloeng letsoai bismuth sebediswa bakeng sa kalafo ya mafu gastrointestinal, pele ke ahlamisa Helicobacter pylori. metsoako tsena ke manganga ho tikoloho asiti ea mpeng. metsoako Bismuth ka mucosa senyehile holim'a ya ho theha e filimi sireletsang tloha tikoloho e senyang, fokotseha acidity le ho kgothaletsa scarring pele tsa bokaholimo ameha.

Ha u bula Helicobacter pylori metsoako bismuth o ile a bontša le phello e hlollang le ka hatelloang le ho timetsoa ha ea libaktheria ena e khethehileng.

Formulations sekoting sehlopha sebediswa bakeng sa a fele le

proton e pompa inhibitors (PPIs) ke bohlokoa haholo e ka phello rarahaneng ka Helicobacter pylori. PPI lithethefatsi na le ea mofuta ofe e le hantle antacid, fokotsa aggressiveness ha tikoloho acid e. Libaktheria Liphuputso li bontšitse hore ho tsoa tikolohong asiti e e-shoa. Kahoo, PPI bopa maemo a sa mamellehe ho phutholohile teng ea libaktheria e rarahaneng le bismuth, "metronidazole" le eketseha lithibela-mafu katleho fele tsa Helicobacter pylori ho 95% le ka holimo. meriana Tsena li akarelletsa:

• "Omez" ( "omeprazole");
• "Nolpaza";
• "Rabeprazole";
• "Pantoprazole" joalo-joalo.

e leng "Omez" abeloa khafetsa. Blockers kapa proton e pompa PPI liehisa mosebetsi oa secretion ea litsoelesa tshilong ya dijo.

Tlwaelegileng a ea tse silang lijo pampitšana microflora ka mor'a fele tsa Helicobacter

Ke Kopana le lithibela-mafu ka maemong a mangata, ke kotsi ho mala le mala. Ka lebaka leo, ka mor'a mekgwatshebetso ya ho hlokahala ho fokotsa tšenyo e fele bakileng ho 'mele. Ho etsa sena, ho na le tsena e molemo lihlahisoa tse kang probiotics kapa prebiotics, le tla bontshwa ka dysbacteriosis, flatulence, letšollo, joalo-joalo tsena li kenyeletse .:

• "Laktoferon";
• "Linex";

• "Hilak Forte";
• "Bifidumbacterin";
• "Atsipol" joalo-joalo.

Probiotics le Prebiotics - tlwaelo ho feletseng fapaneng, ka tumellano complementing mosebetsi e mong le e mong. lihlopha tseo ka bobeli ba le liphello tse molemo ka phelang ka ho normalizing le limela mala. Phapang pakeng tsa bona ke hore probiotics - phelang setso sa microorganisms molemo. Prebiotics tšoanang - manyolo metsoako lik'hemik'hale. Pele ka ho toba "hōle" le microflora bafu, bobeli - ho etsa maemo a molemo bakeng sa sena. Ba sebele lokela ho nka ka mor'a fele.

thibelo lefu

Helicobacter pylori latent microcyteme ka 'na ba e mong le e. The kokoana-hloko e phela ka mpeng, intestine le molomo cavity tsa batho kapa phoofolo ka lilemo tse ngata 'me ha a iponahatsa.

Tshebediso ya ea libaktheria le hlaha ka lebaka la ho ya ho hloleha boitshireletso tlas'a khatello ea kelello, mekhoa e kotsi (joala, ho tsuba), seratsoana sa leka-lekanang 'me bohloko epigastric bontša ka boeona. Mefuta e meng ea Helicobacter ka ama sebete.

bofello

Silafatsoa tšoaetsong ea mecha ea phatlalatso e hlaha ke ka ikopanya le kapa ka tšebeliso la lihlooho tse ruuoang. O lokela ho ka hloko latela melao ea bohloeki ea botho, e le hore ho fokotsa ho silafatsoa tsa karolo ea boraro-e mengata. Ebe ha ho hloka fele tsa Helicobacter pylori.