Pathogenicity le virulence ea microorganisms. Virulence - ho ...

'Mele oa motho ke lehae la ka 100 trillionov libaktheria. Bo-rasaense ba kajeno ba feela hona joale oa hlokomela hore kamoo tsena baahi rarahaneng kopana le motho eo. Ba ama tshebetso ya ho tshilo ya dijo, boitshireletso ba mmele 'me mohlomong le esita le ka kelello boiketlo. Leha ho le joalo, ha libaktheria tsohle tse ka coexist le 'mele oa motho ka khotso le kutloano. E bitsoa pathogenic kokoana-hloko e ka etsa hore lefu ka limela, liphoofolo, kapa likokoanyana. Likokoana-hloko bontša pathogenicity bona ba sebelisa virulence. Ho joalo, seo ke virulence?

Khopolo ea virulence

Virulence - ke nako ea ho hlalosa tekanyo ea ho pathogenicity ea kokoana-hloko e. Ka lebaka leo, determinants tsa virulence tsa pathogen ke e 'ngoe ea, libōpeho tsa lona liphatsa tsa lefutso skeletal kapa mehaho e lumella lefu le lona.

Kamano pakeng tsa makhotla le pathogen kamehla matla, hobane e mong le e ka fetola mosebetsi e le mesebetsi ya tse ling. Sephetho sa kamano e itšetlehile ka virulence tsa pathogen le tekanyo e lekanyelitsoeng ea ho hanyetsa kapa susceptibility ba moamoheli ea. Karolo ea bohlokoa o boetse o bapetse katleho ya mekgwa e sireletsang ea phelang.

lintlha Virulence amana ka ho toba le thepa e lumella microorganisms kotsi fumana ka kapa ka 'mele oa makhotla le sesosa lefu. Tsena li akarelletsa chefo baktheria e tlatsetsang ho pathogenicity ena.

lintho tsa bohlokoa

Invasiveness - sena leseli ka dinama tse nyenyane tse ka. Ho akarelletsa ho mekgwa bakeng sa kolone khoneha le tlhahiso ea dintho kantle ho sele eo kenya letsoho hore ho ka monyetla oa ho a hlasela le ho circumvent kapa hlōla mekgwa itseng a ho sireletsa.

Toksogennost - le matla a ho excrete chefo. Libaktheria li ka hlahisa mefuta e 'meli ea chefo: endotoxins le exotoxins. Exotoxins lokolloa liseleng tse baktheria le ho kgothaletsa kgolo ya libaktheria. Endotoxins ba seleng ea ntho.

chefo baktheria, bobeli qhibilihang ka har'a 'me li-cell amanang, ka isoa ka mali le lisele tsa mmele dinama tse nyenyane tse le ho etsa hore litla cytotoxic libakeng tsa mahaeng ho tloha ntlha ea pele ea ho kenella ka hare. Itseng baktheria chefo e ka boela bōpa le likolone ho ba le seabo tlhaselo ena.

Pathogenicity le virulence ea microorganisms

Pathogenicity - bokhoni ba e phelang ho baka lefu. Bokhoni bona ke liphatsa tsa lefutso karolo ea pathogen, e leng Harms lehlakoreng moamoheli. Bakeng sa likokoana-hloko monyetla, bokhoni ena ho etsa hore lefu ha se tlhaho. Likokoana-hloko ka ntša e mengata e fapaneng virulence.

Virulence - khopolo e inextricably amahanngoa le mohopolo wa pathogenicity. Tekanyo ea ho virulence tsa pathogen e hangata correlated ena le bokhoni ba ho ikatisa ho moamoheli le ka 'na ea itšetleha ka lintlha tse itseng. virulence lintlha kenya letsoho hore ho pathogenicity e, ke hore, ho thusa ho etsa hore lefu.

Likokoana-hloko

Batho ba bangata ba ho pheta-pheta ba huleloa hloko litsebiso tse sa tšoaneng tsa lipapatso sehlahisoa a ipolelang hore bolaea 99% ya likokoana-hloko. Pathogen - e leng lentsoe le sebelisoa ho hlalosa lintho tse nyane (libaktheria le likokoana-hloko), ho etsa hore mafu a sa tšoaneng. Ka terminologicos tsa likokoana-hloko, e boetse e tsejoa e le moemeli causative. Ho na le mefuta e 'maloa ea likokoana-hloko tse bakang mafu a sa tšoaneng ho tloha ho ba tloaelehileng batang le ho ipolaea kankere.

microorganisms Pathogenic ama motho ka litsela tse ngata, ho itšetlehile ka virulence bona. Virulence - e leng lentsoe le sebelisoa ho hlalosa ho atleha ha e pathogen ho khetheha. The pathogen feta virulent e, le ho feta ho tla ba le tšusumetso e mpe bophelong ba batho.

Lintlha tsa virulence

Virulence lintlha ho na le lihlooho likokoana-hloko hore akanya hore nang le tsona pathogen virulence. The feta moo, ba boholoanyane monyetla hore e tla ba sesosa sa lefu lena. lintlha tsena fa molemo ha ba sebetsana le tsamaiso ea batho boitshireletso, 'me le ho feta ka ho eketsehileng, ba e ka ba kotsi.

Ho na le mefuta e 'maloa e fapaneng ya lintlha virulence hore a ka ba teng kapa sieo ka pathogen ho khetheha: lintlha tsa kolone, enterotoxins le hemolysin. Virulence - ke tšobotsi ditirisanommogo, e emelang tekanyo ea lefu le bakoang ke kokoana-hloko e itseng. Tsobotsi ena, e bontša le tirisanommogo magareng a e pathogen le microcyteme. Virulence hangata correlated le bokhoni ba pathogen ho li atile '. Sena se le ka itšetleha ka microcyteme le lintlha tikoloho.

A pathogen baktheria hangata hlalosoa e le baktheria efe kapa efe eo ke nang le bokhoni ba ho baka lefu. matla a ho baka lefu o bitsoa likokoana-hloko. The virulence ea kokoana-hloko ke ka ho toba itšetlehile ka mofuta wa tshwaetso le ho ke pontshi tsa ho tiea ba lefu lena le hore ao bo a bakang.