Moriana o 'Neostigmine'. Litaelo tsa tšebeliso

Ho lokisetsa "Neostigmine" (matlapa, liente) amana inhibitors tsa cholinesterase. The a sebetsang a lithethefatsi motsoako - methylene sulfate neostigmine.

Lithethefatsi ama haholo-holo ka tsamaiso ea pheriferale, ka thata phunyeletse ka mali-boko mokoallo. Bontšang lithethefatsi "Neostigmine" litaelo bakeng sa ho sebelisoa e bua ka bokhoni ba lona ho fokotsa khatello ea intraocular, narrowing ea barutoana ba. Ho bolela qholotsa ho eketseha ha molumo le contractility mesifa boreleli ea tsamaiso tshilong ya dijo, senya bronchial le mosese, e etsa hore bradycardia, spasm ea tsa bodulo. Lithethefatsi kgothaletsa ho mofufutso, mathe le litsoelesa tse ling tse amanang endocrine tsamaiso, e khothalletsa nolofatsa ea phetiso neuromuscular Leha ho le joalo maemo phahameng e ka etsa hore thibelo ea eona.

The litekanyetso li behoa phekolo ea lithethefatsi "Neostigmine" ha e ba le tšusumetso e bohareng. Ketso ea lithethefatsi o ile a re ka mor'a metsotso e mashome a mabeli ho mashome a mararo, etsahalang bakeng sa tse peli le halofo - lihora tse 'nè. Bolela mahloriso lebetsoeng le e ile ea fihla ka mor'a lihora tse 'ngoe ho tse peli.

Lithethefatsi "Neostigmine". kopo

O ile a bontša moriana o ha mafu dilenaneo e loketseng ho mo ntša kotsi boko, ho ruruha ha boko, poliomyelitis, meningitis, shoele litho. ho bolela ka abeloa hape ka bothata myasthenic, myasthenia gravis, atony (senya, intestine, mala). Ke bopaki ba lithethefatsi "Neostigmine" litaelo bakeng sa ho sebelisoa le nkang e felloa ke matla a optic methapo ea kutlo, neuritis, glaucoma. moriana o sebelisoa e le pheko ea ho relaxants mesifa.

Dropwise laolwa letsatsi ka 0.5 mg, hanngoe kapa habeli ho batho ba baholo, bana ba - ka selemo bophelo ba ya 0.05 mg, (empa ha le leholo ho 0,75 di ml tharollo ya 0.05%).

Ka hare ho kgothaletswa ho nka letsatsi ho 0.015 g, ho tloha linakong tsa tse peli ho tse tharo. Nako ea phekolo - mashome a mabeli a metso e mehlano - matsatsi a mashome a mararo. Haeba ho hlokahala, botjha kalafo karohano pakeng tsa kalafo dithuto - libeke tse tharo ho isa ho tse 'nè.

Contraindications ho setsing "Neostigmine" litaelo bakeng sa ho sebelisoa e kenyeletsa phetha molao obstruction tsa pampitšana mosese kapa mantle a, peritonitis, ho se mamellane ka bomong. Se khethoe moemeli bakeng sa atherosclerosis, angina, le asma e, hyperkinesis, lefu la sethoathoa. U se ke ua noa meriana e nakong ea bokhachane le ho diabolololo.

Tlatsetso liphetoho bohloko ha ba sebelisa thero "Neostigmine" taeo pukwanana o re ho nyekoa ke pelo, e ile ea eketseha peristalsis le phokotso spastic ka intestine, hypersalivation (ka tsela e feteletseng salivation). The liponahatso mpe hape e kenyeletsa arrhythmia, meferefere bonwang, tahlehelo ea kelo-hloko, bofokoli, fainting, molikoalikoane, ho atrioventricular le literata, ho otsela. Lithethefatsi "Neostigmine" e ka boela ea baka matlafatsang bronchial le pharyngeal maro, hypotension, cardiac tšoaroa. liponahatso bohloko kenyeletsa le kulisa, e ile ea eketseha ho fufuleloa, khafetsa ho ntša metsi, arthralgia, dysarthria, tsitsipana, spasms ka mesifa ya marapo (ho akarelletsa le puo ea musculature), tremor, bronchospasm, thibelo (ho fihlela ho e setopong) hema, wheezing.

Overdose lithethefatsi "Neostigmine" o ile a bontša khafetsa ho ntša metsi, letšollo, e ile ea eketseha motility, ho nyekoa ke pelo, cramps, cholinergic maqakabetsi. Ho feta moo, ho na le e twitching mesifa ya marapo le mesifa leleme eketseha mesifa bofokoli, e leng e sebetsa ho mesifa ea matšoafo. Ho imolla matšoao a e overdose ea phekolo "Neostigmine" taeo ka kgothaletswa tsamaiso metatsina, atropine le mahlahana a mang limithara-anticholinergic.

Re lokela ho hlokomela hore ente ea lithethefatsi "Neostigmine" ha feela sebediswa ea ho phekola batho ba, empa hape liphoofolo. Ka moriana a diphoofolo, pheko e hlophisitsweng bakeng sa maloetse a ya mesebetsi tsa likoloi.

Pele e sebelisa "Neostigmine" ke ke ho hlokahala hore a bale ngaka le hlahloba kakaretso.