A pheko bakeng sa lefuba. New-ba khahlanong le TB lithethefatsi: lebitso, litaelo

lefu lefuba o bitsoa tlhaho a tšoaetsanoang, le bakoang ke Mycobacterium (wand Koch) le ponahalo o tloaelehileng haholo oa diriswa methapo. lefu kalafo lokela ho akaretsang, e tsoelang pele, e kenyeletsa lithethefatsi 'maloa-ba khahlanong le lefuba, a fuoa nahanela ya pathogen ena.

lithethefatsi sehlopheng

E mong le e moriana TB ke karolo ea sehlopha se itseng ea thepa. kabo ena e thehiloeng lik'hemik'hale, mosebetsi ea tleleniki le tolerability bakuli:

• letoto la pele ( "Inh" "Rifampicin") - e atlehang ka ho fetisisa;
• mola bobeli ( "streptomycin", "Kanamycin") - le bokgoni karolelano;
• mola boraro ( "Thioacetazone" "Lebakeng") - tse sa sebetsa.

lithethefatsi Haholo e atlehang li sebelisoa hangata ka ho fetisisa ka ho kopantseng e mong le ba bona ba le mokhoa oa ho lihlopha tse ling. Matlapa a setseng ke lefuba bitsoa bekapo. Ba sebelisoa maemong a moo pathogen e manganga le metsoako mafolofolo tsa moleng pele.

"Inh"

Lithethefatsi "Inh" e sebediswa ea ho phekola ba batho ba baholo le bana. bohato lona e lebisitsoe ho foromo mafolofolo pathogen ena. Mabapi le mycobacteria ea ka boemo ba ba bang kaofela, o ile a ke thuso. Sebopeho sa khetla Koch wand akarelletsa ho mikolievaya acid e, eo tswakana e hatella ke lithethefatsi.

"Isoniazid" - pheko ea lefuba libakeng tsohle le mefuta e. litekanyetso li behoa e fetola batho ka bomong, ho itšetlehile ka joang, le hore na ho bolela oa setsebi o buella e ho lokisetsa hlakanywa.

1. "Isoniazid" + "Rifampicin" - tsela ea kalafo etsahala fetang libeke tse 6 kapa 8. Lithethefatsi e nkiloeng hang letsatsi le letsatsi hoseng ka mpeng letho.
2. "Isoniazid" + "Thioacetazone".
3. "Isoniazid" + "Rifampicin" + "pyrazinamide" - ka joalo sesebelisoa motswako o bitsoa "Rifater". Sebetsa ka likhoeli tse 2 ka letsatsi le letsatsi, ho eketsa ho atleha ha kalafo, "streptomycin" kapa "ethambutol".
4. "Isoniazid" + "Ethambutol" - TB moriana ka tokiso phekolo.

"Rifampicin"

Features ya lithethefatsi "Rifampicin": litaelo bakeng sa ho sebelisoa (mokgwa wa theko - tse 200 li-ruble) e bolela hore ntho e atlehang ka ho khahlanong mycobacteria ka sebakeng se amehileng, e fihla ea mahloriso lebetsoeng le teng. TB likokoana-hloko le tšekamelo ea ho ka potlako fumana e sebediswa ho eona, ka lebaka la seo lithethefatsi ke e fokolang. Ha sebelisoa nakong ea kanyeso, hobane o na le thepa ea ka bongata ka lebese.

"Rifampicin", litaelo tsa tšebeliso, theko ea tse ho tse thathamisitsoeng leqepheng libaka tse khethehileng meriana na litla-morao, hlahisa e bolela tse latelang:

• cephalalgia (hlooho);
• reversible renal ho hloleha (tshebetso renal recovers mor'a tsamaiso lithethefatsi);
• kulisa;
• dyspeptic matšoao a - ho hlatsa, letshollo, bloating;
• thothofatsang Pono;
• liphetoho entsprechen laboratori ea mali pheriferale.

le para-aminosalicylic acid e

"Lebakeng" - pheko ea lefuba e thehiloeng amino acid e salicylic. E ya hlahiswa ka sebōpeho sa lipilisi, tharollo, granules. The litekanyetso li behoa ea letsatsi le letsatsi e arotsoe tekanyetso 3 e amohetsweng, ho noa lebese, metsi matsoai, fokolang soda tharollo. Maemong a mang, ngaka alakisi ka lethal dose ea letsatsi ka mohato o le mong.

ho lokisetsa e ka mokgwa wa ho intša abeloa, eseng feela ka hammoho le oa mahlahana a tse ling tse-ba khahlanong. E sebetsang feela ho mahlahana a le, ba le boemong e sebetsang. Ho hanyetsa ea mycobacteria ho ntho mafolofolo nakong e hoo e batlang e sa pele.

"Pyrazinamide"

Matlapa a lefuba amanang le lithethefatsi maiketsetso bobeli-line. Le sebelisitsoe ka ho kopantswe kalafo ea lefuba ba selegae le efe kapa efe. Sebelisa "pyrazinamide" nakong ea bokhachane le ho diabolololo ke khoneha, ha feela hore mycobacteria tse manganga lithethefatsing tse ling tse atlehang haholoanyane.

Hang ka khoeli e lokela ho leihlo transamiaz boemo ba 'me ho ba teng ha acid e uric ka mali nakong ea nako e telele moemeli kalafo. Contraindications ho sebelisoa ka tsona ke tsena:

• hypersensitivity motho ho e ntho mafolofolo nakong;
• matla renal tsamaiso e khopo;
• manyolo bolwetse ba sebete.

fluoroquinolones

Lithethefatsi sehlopheng e sebelisoa e le kalafo e bakang. chelete e ba le phello e bactericidal, amang mycobacteria phomotse le nakong ea mosebetsi.

"Ciprofloxacin" buelloa hammoho le lithethefatsi tse ling tse-ba khahlanong le lefuba. Palo e kahodimodimo ea mahloriso 'meleng e fihlellwa ka hare ho lihora tse seng kae ho tloha mehleng ea baeti ba fihlelang ho. E ka etsa hore mafu a letšollo, cephalalgia, ho tšoenyeha kulisa, fokotseha bonwang acuity.

"Ofloxacin" - pheko ea lefuba, eo e ama lefelo la DNA e liseleng tsa pathogen ena. Ho fumaneha ka matlapa a le tharollo bakeng sa Infusion. The lethal dose ea letsatsi le letsatsi e fumaneng ka mehato e 'meli e nang le dikgao 12-hora. Sena se etsa hore ho ka khoneha ho kamehla ho boloka ea mahloriso hlokahalang tsa "ofloxacin" ka 'mele.

"Lomefloxacin" - ya lithethefatsi e atlehang e hoo e ka bang 100% bioavailability. Ho bolela ho "ho sitisa" ka DNA ea pathogen le ketane 'na sebakeng sona ka seleng. Contraindicated nakong ea bokhachane, diabolololo, bana ba ka tlaase lilemo tse 18.

meriana e mecha

Dipopontshwa tšimong ea TB tse amanang le tsoelo-pele ea bohlokoa haholo e atlehang lithethefatsi-ba khahlanong le lefuba, le nahanela tsa likokoana-hloko ho eo o ne a ke fokotseha ka nako e telele ea nako.

lithethefatsi New khahlanong le lefuba:

• "Perchlozone" - lithethefatsi o na le toxicity tlaase ho 'mele oa motho, leha ho le joalo, ke motho ea mafolofolo haholo khahlanong mycobacteria. Contraindications kenyeletsa bokhachane, diabolololo, boseeng, hypersensitivity motho, a liphio le sebete bolwetse.
• "Mikobutin" - nkiloeng antibacterial moemeli rifabutin sebelisoa ho alafa liforomo foleng ba lefu lena le bakuli ba nang le manganga ho "Rifampicin". E e sebediswa eseng feela e le phekolo e, empa le bakeng sa tsa thibelo ea mafu.
• "Bedakvilin" ( "Sirturo") ke popontshwa le mokhoa oa ho hatella ho hlahisa enzyme bohlokoa ea Mycobacterium lefuba. E sebetsang hantle ka mor'a likhoeli tse 3 tsa kalafo (bapisoa le lithethefatsi tse ling bontša lebaka le ka lilemo tse 1.5-2), ho fana ka sephetho mpe teko.

Lehlakoreng liphello tsa phekolo

The ketsahalo tsa litla-morao ka lebaka la 'nete ea hore le lithethefatsi o ile a sebelisa haholo ama le thulaganyo tshilong ya dijo tse etsahalang ka mamello,' me a etsa hore tsoelo-pele ea mafu hypo- kapa khaello, mafu dithulaganyo redox.

Liphello atileng ka ho fetisisa-morao tse:

• utloa ke tahlehelo;
• polyneuritis pheriferale;
• kholofalo ea mosebetsi wa litho tse ka sehloohong le tsamaiso ea;
• kulisa;
• goiter;
• candidiasis;
• dyspeptic matšoao.

A ponahalo itseng tsa Jarisch-Herxheimer itsoara joang ka - e le karabelo ea mamello ho timetsoa tsa litonanahali tsa mycobacteria ka matsatsi a seng makae pele ka mor'a ho qapa phekolo.

Folk meriana bakeng sa lefuba

Ka nako e telele kalafo ea bakuli ikemiselitse ho leka ho bolela leha e le efe, e le nako e telele ha ba ntse ba potlakisa tshebetso pholiso. maloa ba diresepe hore eketsa ho atleha ha phekolo ea lithethefatsi.

Thispone tsa birch buds tšela linoelo 2 hlapolotsoeng ho noa joala kapa vodka. Tsitlella ho fihlela ho fihlela tharollo e tla ba cognac mmala. Nka thispone makhetlo a 3 ka letsatsi ka nako ya tsela eohle ea phekolo.

Reed siea itlhatsoelitseng, e omeletseng le sile, ba ileng ba tla ho tsoa 3 tablespoons. Tšela dikopi tse 2 metsi, pheha bakeng sa metsotso e 5-7. Ho tsitlella le mathata. Noa 1/2 senoelo sa mokelikeli pele e mong le e ja lijo.

Pela mafura, mahe a linotši le walnuts - meriana setso bakeng sa lefuba, ho atleha ha eo e itšetlehile ka ha e kopana le le letona. E sithabetseng linate le peretaplivaetsya mafura. metsoako tsohle li tsoakane ka boholo lekanang. motsoako o kenngoa ka molomo le ema ho fihlela a e qhibilihile.

Pine kapa phaene amohang tšela joala 2-2.5 cm, ka holimo le capped. Matsatsi a seng makae hamorao le tharollo fetoha homogeneous. Ena e ile a phaella ka ho lard qhibilihile le mahe a linotši kalaka ka tsela e lekanang. Nka teaspoon ka makhetlo a mararo ka letsatsi bakeng sa likhoeli tse tšeletseng.

E lokela ho a hopola hore tšebeliso ea mokhoa ofe kapa ofe le litokisetso tla etsahala tlas'a bookameli ba litsebi le ba tšoanelehang.