Tioktatsid®: analogues. Tioktatsid®: amohele taeo, theko, ulasan pelanggan

Tioktatsid® - thioctic ho lokisetsa (jwalo ka e bitsoa, alpha-lipoic acid). Alpha-lipoic acid e - e matla antioxidant, ke karolo ea bohlokoa ka liphetoho tse ngata skeletal le dithulaganyo fisioloji ka 'mele oa motho, e leng se ka tlas'a maemo a tloaelehileng' me e hlahisitseng. Thioctic asiti mosebetsi ke ho sireletsa lisele tsa 'mele liphellong tse senyang tsa radicals free. Ho feta moo, acid e thioctic fapane mosebetsi detoxication le ho akarelletsa ho tsosolosoa ha le e se nang sesosa antioxidant tsamaiso e khopo 'meleng. Ka ho khetheha, alpha lipoic acid e di hlohleletsago tsosoloso ea vithamine C le E, coenzyme Q10, eketsa ea mahloriso tsa ka hare antioxidant glutathione.

Tioktatsid® le mosebetsi nootropic, ho sireletsa sebete, ho fokotsa ea mahloriso ea lipids mali, ho akarelletsa le k'holeseterole e, di hlohleletsago tsoekere tshebediso ke lisele tsa 'mele, kahoo fokotsa boemo ba lona maling. Phello ea fokotseha joalo fetoha rarahaneng tšusumetso e liponahatso tsa 'mele ka insulin ho hanyetsa. Tioktatsid® hape ho fokotsa tlala, di hlohleletsago okisleniyae acid tse mafura, ka tsela eo ho thibela ho bokella mafura a 'mele' me o tlatsetsa ho tlwaelegileng a ba boima ba 'mele, ho akarelletsa le kalafo ea botenya.

Tioktatsid® BV (ka potlako ho lokolloa) - lithethefatsi ka ho khetheha e le litekanyetso li behoa foromo e optimized e le hore nka e ka molomo. Joalo sebopeho sa etsa bonnete ba hore 'mele oa tla etsa e itseng eo di ea acid e thioctic, boemo ba lona ka lero la mali mali ho ba tsitsitseng. Ho phaella moo, ka potlako ho lokolloa foromo e fana ka bioavailability phahameng ea boleng bo sebetsang.

The pharmacokinetics ea lithethefatsi Tioktatsid®

Ka lebaka la sebōpeho khethehileng sa tokollo hang-hang, o ile a ke le 'mele-alpha, lipoic acid e ka nako lekgutshwane ya metsotso 15-20, feletseng ananelang ka mali ho tswa ho pampitšana ea pele tshilong ya dijo. E lokela ho a hopola hore e tsoa hong ho amohelloang Tioktatsid® BV le lijo haholo ama absorption ea chesehang ea mafolofolo motsoako (alpha lipoic acid). Latelwa le likhothaletso tsa baeti ba fihlelang ho ea lithethefatsi - tsa mokete oa ka mpeng letho halofo ea hora pele lijo - ho thibela sebelisana sa batleheng le lijo, tabeng ena, tshebetso ya ho absorption ea acid e, alpha-lipoic ka mali ka nako eo lijo e se e phethiloe. Palo e kahodimodimo ea mahloriso ea acid e thioctic ka lero la mali mali fihla metsotso e 30 ka mora moriana e fetile, e 4 ug / ml tse, moo ho alpha lipoic acid e, tšoauoa ka phello ea "fetisetsana pele" ka sebete. The bioavailability alpha-lipoic acid e moketeng oa lenyalo Tioktatsid® BV paakanyong ke 85%. Litsela tsa sehlooho tsa metabolism 'meleng - ho kena moea le conjugation. Ho fihlela ho 90% ya acid e thioctic le lihlahisoa tsa lona metabolism felisoa ka tsela liphio. The halofo bophelo bo metsotso 25.

Ho bonahala le lefu la tsoekere le joala polyneuropathy

asiti Thioctic e kenyelelitsoe ho phekola maemo a mafu a tse latelang: neuropathy amanang le systemic mafu connective dinama tse nyenyane tse. Radiculopathy. Parkinson lefu. Leqeba. Bongata ba kokwanahloko hepatitis A le C le maikutlo a ho tiea e leka-lekaneng. Lefu la tsoekere foufatsang le macular edema.

Contraindications ho lithethefatsi Tioktatsid®

Ho letsatsi ho na le ho na ya data ka tšeptjoang ka phello ea lithethefatsi 'meleng oa mosali nakong ea bokhachane le ho diabolololo, kahoo bakuli joalo Tioktatsid® se abetsoeng. Ka lebaka le tšoanang le e sa kgothaletswa ho sebelisa lithethefatsi ho tšoara bakuli bao lilemo e ka tlase ho dilemo tse 18. Hypersensitivity ho dikarolo tsa moriana o boetse o contraindicated.

Kopo, ka litekanyetso li behoa ea moriana Tioktatsid®

The lethal dose ea letsatsi le letsatsi ha ingested 600 mg, ea lithethefatsi (tse Letlapa le nngwe). Nka moriana tieo ka mpeng ea lefeela, halofo ea hora pele lijo tsa hoseng. Letlapa le metsitsoe kaofela ntle ho hlafuna, hlatsoa fatše ka metsi. Ha nyeoe e 'ngoe e e-ba boima, o ile a sebelisa ho tšoara Tioktatsid® 600T ne a rerile hore tsamaiso intravenous. Letsatsi le letsatsi le mamello e laolwa ke dikahare lieha intravenous tsa vial mong (600 mg,). Therapy nka ho tswa ho libeke tse peli ho isa ho khoeli, 'me joale ile a etsa kopano le phetolelo le mamello Tioktatsid® BV. Ho thibela liphetoho tse sa rateheng tsa ente e lokela ho fanoa ka tharollo bakeng sa bonyane 12 mets.

Ho tloha ka ho nka bohato lithethefatsi karolo nahanela fapaneng ho tla leseling, vials tlosoa lebokoseng le hang-hang pele ho tsamaiso ea lithethefatsi. Ka mor'a moo, mamello e isoa phekolo lithethefatsi Tioktatsid® DB 600 ka lethal dose ea la 1 Letlapa ka letsatsi.

Le litla-morao tsa lithethefatsi Tioktatsid®

Ka lehlakoreng la pampitšana gastrointestinal hangata e tšoenyehile ka nyekeloa ke pelo. liponahatso tse ling tsa boemong bo sa thabiseng ka lehlakoreng la tsamaiso tshilong ya dijo - ho hlatsa, bohloko ka boqapi ba ea mala le mala, litulo hlephileng, phetoho ka tatso - ba tšoenyehile, maemong a sa tloaelehang haholo.

kulisa (letlalo ho hlohlona, rashes ka 'mele, hives, anaphylactic makala) ka seoelo itšoenye.

From tsamaiso ea methapo e ka ho ameha ka ho tsekela.

Akaretsang: maemong a sa tloaelehang haholo, ka lebaka la ho tlhotlheletso ya dithulaganyo tsoekere lahla ka ba ferekanya matšoao a hypoglycemia (Pono lerootho, ho fufuleloa, hlooho e opang, pherekano), e ke ka lebaka la ho fokotseha ka maemo tsoekere mali.

Tioktatsid® ditshebeditsano lithethefatsi le lithethefatsi tse ling

Ha ea lithethefatsi e sebediswa hammoho cisplatin, cisplatin attenuated.

Ho tloha ka acid e thioctic, eo na le Tioktatsid® BV Tioktatsid® 600T, khothalletsa batho tšepe tlama e sa kgothaletswa ka nako ka litokisetso tšepe. The karohano pakeng tsa baeti ba fihlelang ho Tioktatsida® le litokisetso tšepe, k'halsiamo, boselamose e lokela ho ba bonyane lihora tse 2. Maemong a moo Tioktatsid® sebelisoa ka nako le mahlahana a molomo hypoglycemic kapa ka insulin, phello hypoglycemic ba mahlahana tsena e ka hlaha ho feta bitsoa. Ho ke ke ho hlokahala ho hlokomela diteng tsa tsoekere maling, haholo-holo karolong e qalang ea kalafo.

lemosa

ho lokisetsa e ka capsules ha a pepesa ho tla leseling fihlela tšebeliso e tobileng. Nakong ea kalafo lokela ho lahla ho sebelisa ethanol, e ea bobeli e ka nna ya le palokatiso tlatsetsang ntshetsopele ya polyneuropathy.

Analogues, theko, ulasan pelanggan ka lithethefatsi Tioktatsid®

Tioktatsid® boleng ka mokgwa wa ampoules e ka 1500 li-ruble tse tlang e le matlapa a -. 1700-3200 li-ruble. Ka ho fetisisa chelete e ngata ambalaji - 100 lipilisi likhoeli tse tharo.

Tioktatsid® - kajeno lithethefatsi feela le ka potlako ho lokolloa foromo eo e fana ka absorption palo e kahodimodimo ea lithethefatsi a sebetsang a 'mele.