Monocytic ehrlichiosis motho: phumano le kalafo

Monocytic ehrlichiosis motho - ena ke ka seoelo a tsoaetsanoang bakoang ke libaktheria tsa lelapa Ehrlich. Bolwetse ka bontša keketseho e bohale ka mocheso oa 'mele, hlooho e opang, bohloko mesifa (myalgia), chills, unexplained mokhathala, bofokoli. Symptomatology e hlokometse ka libeke tse 'maloa ka mor'a tshwaetso e ka lekhetlo la pele. Ho feta moo, maemong a mangata, e le ka lebaka la liteko tse laboratori ea senola ho fokotseha ha palo ea li-platelet ka e potoloha mali (thrombocytopenia) hammoho le ea fokotseha ka tšoeu count ya seleng ea mali (leucopenia), 'me e leng keketseho e sa tloaelehang ka maemo a itseng enzyme sebete (e amanang le sebete transaminase). Maemong a mang, le matšoao a hatele pele 'me a bolela hore ka ho nyekoa ke pelo, ho hlatsa, letshollo, boima ba' mele, ho lahleheloa ke dikamano tse sepakapakeng. Ha mokuli a e lemoha batho monocytic ehrlichiosis, kalafo lokela ho latela hang ka mor'a hore tepelletse maikutlong, hobane ho ba sieo ha le lefu lekaneng phekolo isang mathata kotsi tse kang ho hloleha renal kapa matšoafo. Bajari ba tšoaetsoa mafu ke mites.

Lipontšo le matšoao a

Monocytic ehrlichiosis motho, matšoao a eo ho ke ho le bonolo ho ho ferekanngoa le matšoao a mafu a mang a tšoaetsanoang, 'me a fumanoa bapisoa tsoa fuputswa. Ka tloaelo ho, ea bolwetse bonahatsa hoo e ka bang libeke tse tharo ka mor'a letshwao loma - Ehrlich libaktheria microcyteme lelapa. Qalong, bakuli ba nang le matšoao tloaelehileng ea tšoaetso, ho akarelletsa le keketseho e bohale ka mocheso oa 'mele le bofokoli kakaretso. Maemong a mang, letlalo lekhopho e ekeletsoa matšoao ao. Ka mafu a tsoaetsanang haholo mokuli ea lahleheloang takatso ea lijo, a lahleheloa ke boima ba 'mele ho itima lijo' me o kotsing ea ho ipolaisa tlala lefu. Ka linako tse ling, ho na le boetse ho na le lipontšo tsa ehrlichiosis a fumanehe ka seoelo - tse kang khohlela, letšollo, 'metso (pharyngitis), le bohloko mpeng.

Maemong a mangata, ha batho monocytic ehrlichiosis e belaela, phumano akarelletsa liteko mali. Diphetho tsa litlhahlobo tsena (motswako leuko- le thrombocytopenia concurrently ka bophahamo e sa tloaelehang ea enzyme sebete) lumella mokuli ho beha tepelletse maikutlong nepahetse. Maemong a mang, ho ba le mamello le tsona le bothata ba ho ruruha sebete (lefu la sebete).

Ho ba sieo ha kalafo e lekaneng ho hlahisa matla monocytic ehrlichiosis motho. Matšoao a boloetse bona mothating ona fapana liponahatso tekanyetso ea tshwaetso le ho e ka ho bontšoa ka liketsahalo tse latelang 'me o re:

• bokhutšoanyane phefumoloho (dyspnea, dyspnea);
• mathata le hoama mali (coagulopathy) hore ho ka etsa hore tsoa mali ho pampitšana gastrointestinal;
• mafu a methapo ea kutlo ka lebaka la ho ba le tshwaetso bokong le lesapong (bohareng tsamaiso ea methapo).

Haeba tšoaetso ea hoholoa sa tsamaiso ea methapo e bohareng, e leng ba le mamello le phumano ea "batho monocytic ehrlichiosis" lemoha sa tloaelehang dinama tse nyenyane tse (hlahala) ka bokong. Ho phaella moo, ka linako tse ling pele meningitis - ho ruruha ea sireletsang lera lera la boko le lesapong la mokokotlo. mokelikeli Cerebrospinal ka boela ra angoa ke tšoaetso.

liponahatso methapo ea kutlo

matšoao a methapo ea kutlo ea lefu lena le kenyeletsa:

• disorientation;
• e sa tloaelehang nahanela leseling (photophobia);
• satalla ka molaleng;
• mananeo a tsa mosebetsi laoleheng motlakase ka boko (sethoathoa);
• coma.
• Maemong a sa tloaelehang, ho na le:
• feteletseng e matla liphetoho reflex (hyperreflexia);
• incoordination tsa mekhatlo boithaopo (ataxia);
• leeme tahlehelo ya bokhoni dilenaneo mesifa ea sefahleho e loketseng ho tshenyo e mong (kapa ho feta) ea lipara leshome le metso e ea methapo ea kutlo tse amanang le boko (palsies cranial methapo ea kutlo).

Monocytic ehrlichiosis le batho granulocytic anaplasmosis ka ho ba sieo ha kalafo litsebi tsa mafu li beha bophelo kotsing.

mabaka a

Mefuta eohle ea ho bolwetse hlahlobisisa bakoang ke libaktheria tsa lelapa la Ehrlich. Pathogen monocytic ehrlichiosis motho o nkoa a mob mobile-negative.

Ho lumeloa hore sesosa se ka sehloohong sa tshwaetso - ya letshwao loma. Tse ling tsa likokoanyana tsena ke bajari ba likokoana-hloko.

Hang 'meleng ka mali, Ehrlichia jala mashano ka mali le lijana lymphatic. Lisele tsa mmele - ka ea 'mele e mokelikeli jereng lisele tse etselitsoeng ho loantša mafu a tšoaetsanoang. baktheria nka lula ba bang ba lisele tse (monocytes le macrophages), e phetha karolo ea bohlokoa haholo ka ho lula re ena le tshebetsong tsitsitseng ea tsamaiso ea 'mele. lisele tse tsena pupetsa libaktheria le sebetswa (thulaganyou e bitswang phagocytosis), ho akarelletsa libaktheria le likarolo tse ling tse tsoang linaheng tse ling. Leha ho le joalo, Ehrlichia phunyeletse tebileng ka tlhaho tshireletso boitshireletso qala ho hōle ka vacuoles - cavities, pota-potiloe ke lera le. Lefu lena le ama feela monocytes le macrophages maling, empa hape mefuta e itseng ea lisele 'mele (ho akarelletsa lesapo moko, lisele tsa mmele nodes, sebete, spleen, liphio, matšoafo le mokelikeli lesapo la mokokotlo).

Differentsiatsialnaya tepelletse maikutlong: granulocytic anaplasmosis

Matšoao a tšoaetso ea sena ka habonolo ferekanngoa le matšoao a pathologies tse ling. Ka ho fetisisa khafetsa differential tepelletse maikutlong ho monocytic ehrlichiosis le batho granulocytic anaplasmosis.

Ho fapana le pasame la, granulocytic anaplasmosis bakoang ke libaktheria le lebitso loketseng ho tse Anaplasma. Kokoana-hloko etsoa ka liboseleise, ama itseng granular lisele tsa mali tse tšoeu - neutrophilic granulocytes. lisele tse tsena ke ka setotsoana tshebetso ya ho phagocytosis le Hangata ke eena ea ikarabellang bakeng sa ho timetsoa ha likokoana-hloko tse kotsi. Ha le tšoaetso ea Anaplasma matšoao a tloaelehileng hangata a bontša ka beke ka mor'a hore boseleise loma - libaktheria transporter. Hoo e ka bang kamehla, ho ba le mamello le bothata ba ho feberu, chills, bohloko mesifa (myalgia), bofokoli kakaretso, mokhathala, hlooho. Ka linako tse ling ho na le boetse ho na le khohlela, ho hlatsa, le / kapa disorientation. Ho feta moo, granulocytic anaplasmosis tšoanang le tshwaetso tse kang batho monocytic ehrlichiosis, ke taba ea hore litholoana tsa liteko le mali a senola keketseho e tšoanang ea itseng enzyme sebete (e amanang le sebete transaminase). Hangata e undiagnosed le khaello ea mali e bakoang ke ho fokotseha e sa tloaelehang ka boemo ba lisele tse khubelu tsa mali ho mali e potoloha. Ho ba sieo ha kalafo e nepahetseng le hlaha kotsing ea ho tšoaroa ke ho hloleha renal. Ka US, maemo a ho batho granulocytic anaplasmosis hangata ho fetisisa e tlalehiloeng ka re ka leboea-bochabela le ka bophirimela.

feberu sennetsu

Monocytic ehrlichiosis motho (pasame la) ho khetholloa hape ho tswa feberu sennetsu - haholo hampe tsebahalang le ka seoelo haholo mafu a tšoaetsanoang bao e leng ea subtype tsa ehrlichiosis batho le bakoang ke libaktheria le ka mokhoa o loketseng e mong ea bitsoang - Ehrlichia sennetsu. Libeke tse seng kae ka mor'a tshwaetso e ka lekhetlo la pele ho ntshetsa pele le matšoao a tšoanang le matšoao a tloaelehileng a pasame la: keketseho bohale mocheso oa 'mele, hlooho e opang, bohloko mesifa (myalgia). Ba bang ba bakuli ba le ho nyekeloa ke pelo, ho hlatsa kapa ho lahleheloa ke takatso ea lijo ho fihlela ho ipolaisa tlala. Ho feta moo, litholoana tsa liteko mali ka bonoa ho fokotsa boemo ba tšoeu count ya seleng ea mali (leucopenia) le keketseho pathological ka bophahamo ba modumo ea enzyme sebete. The microcyteme (kapa microcyteme) feberu sennetsu e ntse e sa toba tse tiisitsoeng; ba bang ba bo-rasaense ba fana ka maikutlo a hore e ka 'na liboseleise, athe, babatlisisi ba tse ling tse re lefu lena e ka ba nang le tšoaetso ka mor'a ho ja tlhapi e tala. Ka nako eo, tšoaetso ne a hlokomela feela ea ka bochabela ho Japane le Malaysia.

Lyme borreliosis

Lyme borreliosis - e mafu a tšoaetsanoang le bakoang ke libaktheria, spirochetes tsa lelapa Borrelia. Bajari vredosnosnyh likokoana-hloko tse Ixodes scapularis. Maemong a mangata, le maloetse ke haholo-holo a bonahalitsoe ponahalo ea ka ho ruruha khubelu ka letlalo, eo ka ponahalo pele joaloka tsosoa chitja letheba la boholo nyenyane (papules). Papule qala ho hōla ka potlako 'me qetellong a fihla disentimetara bonyane tse hlano le bophara ba. Ka mor'a hore ho na le symptomatology, bontšang le monocytic ehrlichiosis motho. Kgonego ya tshwaetso ya Lyme borreliosis ke ka tlaase haholo ho feta mathateng a tšoasa pasame la, empa differential phumano e ntse e le mohato o hlokahala ho fumana tšoaetso. Bakuli ba Lyme borreliosis hape ba atisa ho tletleba ea feberu (ha e le bohale le kotsi, joalokaha e pasame la), chills, myalgia, hlooho e opang, ho fokola, mokhathala, le ho opeloa kapa ho satalla ka manonyello a kgolo (a tšoaetsanoang ramatiki), hangata ka mangole. The symptomatology ka nka sebōpeho sa lipotolohong iphetang. Maemong a matla, ha setseng untreated lemohiloeng mafu a methapo ea kutlo le mafu a ea mesifa pelo. Ho ea ka lipalo-palo, boholo ba Lyme borreliosis e fumanoa ka leboea-bochabela United States. Leha ho le joalo, ho na le maemo a ho tshwaetso le linaheng tse ling, ho akarelletsa le China, Japane, Australia le linaheng tse ling tsa Europe.

piroplasmosis motho

Monocytic ehrlichiosis motho, le monyetla oa ho ba le tshwaetso eo ke batlang phahame ho feta kotsi ea tšoaetso ea le libaktheria tse ling, hase eona feela nang le monyetla kotsi tšoaetsanoang boloetse bo jaloang ke liboseleise. Piroplasmosis motho (ho ya ka dipehelo tse ding - babesiosis) - e tshwaetso bakoang ke dikokwanyana le 'ngoe-e nang le sele e tsoang lelapa la Babesia. Hangata ka ho fetisisa lefu lena le ama le liphoofolo, empa ka linako tse ling ho na le maemo a ho batho ba tšoaelitsoeng ke eona. Ka ho khetheha, ho lumeloa hore le na liboseleise tse bajari ba Babesia hore ka parasitize 'mele oa motho. Piroplasmosis joaloka monocytic matšoao a pele ehrlichiosis motho: bakuli ba tletleba ba feberu, chills, hlooho e opang le bohloko mesifa, ho nyekoa ke pelo, ho hlatsa. Ho feta moo, ho na le liketsahalo tse joalo e sa tloaelehang e le timetsong ea ka pele ho nako ea lisele tse khubelu tsa ajoa mali (haemolytic khaello ea mali), e sa tloaelehang fokotseha ka palo ea tsona (thrombocytopenia), fokotseha ka palo yohle count ya seleng e tšoeu mali (leucopenia), le kholiso ea spleen (splenomegaly). Batho ba nang le matšoao a tloaelehileng le sebelisoang malapeng khotsofatsang bophelo 'na tsa fapana softness kapa le sieo ka ho feletseng. Maemong a e mpe ea 'piroplasmosis motho o ile a re ka ho bakuli ba pele ka buuoa ka makhetlo ho buuoa ho tlosa spleen (splenectomy) kapa ho ba le sesole sa' mele oa fokola. Hangata ka ho fetisisa fumanoa babesiosis batho e ka leboea ea United States, empa ho na le maemo a ho ba bonoa lona linaheng tsa Europe.

American letshwao typhus

Monocytic ehrlichiosis motho tlameha ho khetholloa ho tloha American letshwao ricketsiosis - le ka seoelo a tsoaetsanoang bakoang ke libaktheria tsa lelapa Rickettsia. Vector taolo ke likokoanyana e tšoanang le eo e ka silafatsa batho monocytic ehrlichiosis. Ha typhus hlokomela hlooho matla le opa mesifa, feberu, chills, ho lahleheloa ke dikamano tse sepakapakeng. Maemong a mangata, ka mor'a tse peli - ka matsatsi a tšeletseng ka mor'a hore boseleise loma ha ho sa letlalo lekhopho, haholo-holo ho koahela liatla, manonyeletso, bohato ba maoto, maqaqailaneng le forearms. Hamorao, lekhopho ata ho sefahleho, 'mele o le leoto tlaase. Ka linako tse ling ho na le ho nyekoa ke pelo, ho hlatsa le bohloko mpeng. Maemong a mang, ha lefu lena le ha fumanoa hore o tšoeroe ka nako, kapa ka ho ba sieo ha kalafo e lekaneng, matšoao a letshwao-jere ricketsiosis US ka 'na ba bophelo kotsing. Qhoma ha lefu lena tlalehiloe ka libaka tse fapaneng tsa United States.

tlhathoba

Hlahloba batho monocytic ehrlichiosis, tshwaetso e khona ho etsa hore le matšoao a nang le monyetla kotsi, o lokela ho sebelisa ka ho phethahetseng ho hlahloba ka tsa bongaka, ho hlahloba liteko maloetse-mahala le laboratori ea khethehileng. liteko mali hangata e bontša liponahatso tloaelehileng la batho monocytic ehrlichiosis: fokotseha ha khubelu count ya seleng ea mali (thrombocytopenia), phokotso ea itseng tšoeu count ya li-cell (leucopenia), le tsoa hong ho eketseha ha boemo ba sebete enzyme e itseng (mohlala, serum aspartate aminotransferase le alanine aminotransferase). Maemong a mang, ka lebaka la liteko tse laboratori ea fumanoa pathological cerebrospinal mokelikeli. Ho phaella moo, sefubeng X-ray e ka khona ho utloa liphetoho e sa tloaelehang ka matšoafong (mohlala methapo infiltrates kapa feteletseng mokelikeli bokella).

Ho etsa lipatlisiso mali smear 'tlas'a elektrone-toloki ya microscope khona ho lemoha bokella ea libaktheria e vacuoles lisele tse itseng (haholo-holo monocytes), empa ka mekhahlelo ea pele ea tšoaetso ea lihlopha tse joalo hase kamehla bonahalang. Maemong a mang, tlatsetso liteko tse khethehileng laboratori ea ho fumana hore na mofuta itseng oa tshwaetso le ho netefatsa tepelletse maikutlong ka.

Joalo liteko tse khethehileng kenyeletsa, ho etsa mohlala, e sa tobang immunofluorescence mokhoa bakeng sa e batlang pathologies, e akarelletsa ho ithuta serum hlahiswa motheong oa mali a ka mokuli. Lisireletsi - liprotheine tse hlahisoang ke tse itseng lisele tse tšoeu mali - thusa 'mele oa ntoa e chefo le microorganisms kotsi. Ha u sebelisa e sa tobang immunofluorescence staining tsa lisireletsi itseng batho ngotsweng le lidae fluorescent, serum ile ea behiloeng tlas'a mahlaseli mahlaseli 'me u hlahlobe hore tlas'a microscope ho khetholla karabo ya go arola antibody itsoara joang ho microorganisms itseng.

kalafo

Ha a tiisa phumano ea "batho monocytic ehrlichiosis," ho feta ho tšoara lefu lena? Hangata ka ho fetisisa, lingaka ho laela tekanyetso litekanyetso li behoa ea lithibela-mafu tetracycline. E le phekolo e meng e ka linako tse ling o ile a sebelisa ka lebaka la doxycycline. Maemong a matla, ba ba le mamello 'na ha hlokahala tlhokomelo litsebi ka sepetlele. Ho phaella ho lithibela-mafu, e ka etsahala ho nka tumello moriana ofe kapa ofe ngaka e le hore ba nolofatsa matšoao tloaelehileng sa tshwaetso.

thibelo

Haeba u phela sebakeng hahlaula, e leo ho ahiloeng ho ke liboseleise nang kotsi, ho akarelletsa le bajari ba libaktheria lelapa Ehrlich, ho ke ke tse lakatsehang ho nka mehato e loketseng. Ha o ba siea naha, hopola hore u ka tsela eo hlahisa kotsi ea ho tšoaroa e le bokuli bo tebileng tse kang monocytic ehrlichiosis motho. Photo mites ba tiisa bajari ba libaktheria, e tla lule re falimehile, Leha ho le joalo, ho tseba sera sa ho bokgoni ba ho sa tsotellehe ha hoa lekana. Apara marikhoe a nako e telele, lihempe le T-shirts le sleeveless e telele. Ho bohlokoa ho roala likatiba, molemo ka ho fetisisa - ka bophara-brimmed likatiba, e le mites tse ngata phela ka lifate. Khetha liaparo khanya-mala, kaha e ke bonolo ka ho fetisisa ho bona ke likokoanyana. Sebelisa lisebelisoa tse khethehileng-Keneleng le ba bonnete ba hore ka bobeli letlalo le liaparo, hangata e le ka hlahloba. Fetisisa letshwao longoa etsahala letlalo la hlooho le molaleng.