Lithethefatsi "Gynestril": litaelo bakeng sa ho sebelisoa, analogs le ulasan pelanggan

Tsela ea ho nka lithethefatsi "Gynestril"? Litaelo tsa ho sebelisa moriana ona tla hlalosoa ka thepa ea sehlooho sena. Ho eona, re fana ka likarabo tsa bakuli, lithethefatsi, litšobotsi tse lona diokobatsi, ho bonahala le ho contraindications.

Sebopeho, sebopeho

Seo dikarolo e kenyeletsa meriana "Gynestril"? The Melawana hapa ho ho bolela sena, ho ke ke hore motsoako o lona a sebetsang a ke mifepristone. Hape le moriana o kenyelletsa ditokiseletso metsoako eketsehileng ka mokgwa wa litapole starch, lactose, microcrystalline selulose, povidone, magnesium stearate le starch sodium carboxymethyl.

Reka meriana ena e ka ba ka matlapa a, tse tsa phutheloa ka dipakete tsa lebokoso.

Diokobatsi litšobotsi tse meriana

Na u ne u tseba hore ke lithethefatsi "Gynestril"? Litaelo bakeng sa ho sebelisoa e tla u thusa ho utloisisa molao-motheo oa ketso ea lithethefatsi ena, 'me li tla u bolella hore tlas'a ha ho na matšoao tsa tšebeliso ea eona e ka go ikatisetsa bongaka.

O ne a nka moriana o ke steroid moemeli antigestagens hlahang ho yona a maiketsetso a. The phekolo bohlokwa ba tsamaiso ya moriana ka lebaka la ho sebopeho lona.

Holim 'a fumana mifepristone ka' mele oa motho e thibela liphello tsa progesterone, empa ha e bontša mosebetsi progestational.

Litsebi hlokomela antagonism ea moriana e loketseng ho tlhōlisano glucocorticoid tlama ka boemo receptor.

E le o tsejoa, karolo ka sehloohong sebopeho sa leiomyoma uterine fuoa li-hormone e motšehali, haholo-holo progesterone. Tabeng ena, mifepristone ka abeloa ho ba le mamello ho thibela progesterone receptor. Ka lebaka la kalafo ena etsahala hlahala kgolo ya lieha, hammoho le ho fokotsa boholo ba fibroids , le uterine.

The pharmacokinetic thepa ya moriana

Ke lintho life na le pharmacokinetic lithethefatsi "Gynestril"? Litaelo, ulasan pelanggan phihlelo lingaka re ka mor'a tsamaiso molomo ea mahloriso phahameng ka ho fetisisa ea lithethefatsi e ketekoa hoo e ka bang 80 metsotso. Ho feta moo, bioavailability lona ke 69%.

Lero la mali liprotheine nkoa lithethefatsi tlama ho fihlela ka 98% (ka albumin le Alpha-1 acid e glycoprotein).

Ka mor'a hore mohato kabo le hlaha butle ntsha mohato. Ka ea mahloriso ea mali ea moriana e fokotsehile ka halofo (pakeng tsa lihora tse 15 le 72).

Ho felisoa ha lithethefatsi ke ka potlako, ka e le nako ea lihora tse 18.

ho bonahala

From tseo lithethefatsi "Gynestril" ka abeloa? Litaelo tsa tšebeliso, litsebi li ea sebele bontša le matšoao a kang a latelang:

• kalafo ya leiomyoma uterine;
• qetello ea bokhachane intrauterine ho fihlela ho matsatsi a 42;
• induction (kapa tlhotlheletso) tsa mosebetsi (ho akarelletsa le ho poleloana e reng);
• ithwala (postcoital) bakeng sa unreliability sebediswa dithibela, 'me ka nako e ka mor'a ho kopanela liphate sireletsehang ho kopanela liphate.

Contraindications

"Gynestril" lithethefatsi bakeng sa ho ntša mpa lea lokela ho sebelisoa ha:

• ea bongaka unconfirmed bokhachane;
• lumeletsoe ectopic bokhachane;
• bokhachane eo ho ile ha hlaha ka mor'a a khaotsa ho tsuba ea mokhoa oa hormonal dithibela, kapa ke ho sebelisa e dithibela intrauterine;
• bokhachane ka mor'a matsatsi a 42.

Ha leiomyoma lithethefatsi ena e thibetsoe ho abela maemong a latelang:

• tsamaisa ka nodes submucous myoma;
• ka lihlahala popelo;
• endometrial hyperplasia;
• haeba leiomyoma boleng ke le leholo.

"Gynestril" Tablets bakeng induction tsa mosebetsi ha e sebelisoa ka se:

• haholo preeclampsia;
• e sa tloaelehang fetal nehelano;
• pele ho eclampsia;
• eclampsia;
• preterm kapa poso e telele ea bokhachane;
• lekalekane boholo ba fetal hlooho le bo-'mè noka;
• undiagnosed spotting tswa pampitšana genital nakong emara.

Na kakaretso contraindications lithethefatsi "Gynestril"? Litaelo fana ea potso ena ke e tingwa. lithibelo tsena kenyeletsa maemo a latelang:

• porphyria;
• nako e telele phekolo le glucocorticoids;
• haholo khaello ea mali;
• renal ho hloleheng sebete (foromo efe kapa efe);
• tlōlo ea hemostasis (fetileng anticoagulant kalafo);
• extragenital bo tebileng boo tlhaho;
• bolwetse ba tsamaiso e motšehali ho ikatisa, e leng sebapali se hlabang;
• hypersensitivity (ho akarelletsa le histori);
• nikotinozavisimost, haholo-holo ka mor'a a le lilemo li 35.

Ba hlokolosi feteletseng ha noa moriana ona:

• mafu obstructive methapo (semelo sa foleng);
• pelo ea ho hloleha;
• kgatelelo ya madi;
• arrhythmia;
• bronchial asma;
• pelo ea morethetho meferefere.

Lithethefatsi "Gynestril": setatemente se

Bakeng sa qetello ea bokhachane (ulasan pelanggan ya moriana o ena le mamello li tla tšohloa a batla a ka ho eketsehileng), lithethefatsi ena lokela ho fuoa feela setsebi moqotetsane. Le ntse le se nka matlapa tabeng ena feela ho ba teng ha gynecologist ka.

Ho tloha ka ho sebelisa lithethefatsi "Gynestril"? Litaelo tsa bokhachane qetello e bolela hore ho hlokahala hore ho sebelisa lethal dose 'ngoe ea 600 mg,.

Lithethefatsi e nkiloeng lihora tse fetang 1-1.5 ka mor'a lijo le ho hlatsoa fatse le 100 di ml tse metsi.

Ho eketsa bohlokwa ba tsamaiso ya moriana ka ho eketsehileng mabapi le morero oa 400 mg, misoprostol (i.e., e maiketsetso prostaglandin E1).

Ka mor'a ho amohela matlapa a le mamello tlameha ho leihlo obstetrician bonyane lihora tse peli. Ka mor'a matsatsi a 1.5 kapa 2 etsoa oa ultrasound. Esita le ka mor'a libeke tse 1-2 ho khanna tlhahlobo ea litleleniki tsa le ultrasound maemong a pheta le hlahloba e maling ya hCG ho netefatsa senyeheloa.

Boemong bo joalo, haeba lithethefatsi ba ne ba sa thusa (khr, ho ima ho tsoela pele), ngaka e khothalletsa e lephaka aspiration ho ithuta ka ho eketsehileng (sobotta) liphello tsa ho buuoa hoo ho.

Hore a susumetse mesebetsi e akaretsang, moriana hang tsamaisoa ka litekanyetso li behoa ea 200 mg,. Ba etsa sena ka ho ba teng ha gynecologist ka. Ka mor'a letsatsi le le leng, le lethal dose ea meriana e pheta ka lethal dose e tšoanang.

Ka mor'a matsatsi a 2-3, hakanya atolosoa ha kanale tsoalo. Ka tsela eo fumana le monyetla oa ho sebelisoa ka ho eketsehileng "Oxytocin" kapa prostaglandins.

Ha e le uterine leiomyoma sebelisa lithethefatsi "Gynestril"? Tataiso e bolela hore ha ba lokisetsa ho fumanoe joalo hangata laolwa ka lethal dose e le 'ngoe ea 50 mg,. Lithethefatsi e nkiloeng ka molomo ka likhoeli tse tharo.

Mabapi le lithibela poso-coital, lingaka khothalletsa tšebeliso ea moriana o nkoa ka palo ea 10 mg, ka matsatsi a mararo ka mor'a ho kopanela liphate sireletsehang thobalano (ho sa tsotellehe hore mohato matsatsing). Noa lipilisi tabeng ena ke tse lakatsehang bakeng sa lihora tse peli pele kapa ka mor'a lijo.

maemo a ho overdose

Sebelisa ea lithethefatsi e ho lethal dose e le ba dikgerama se fetang tse peli tsa lisosa tsa litla-negative. Ha u sebelisa tse fetang palo boletsweng ya meriana mokuli a ka theha adrenal insufficiency, e leng hloka phekolo bontshang matshwao.

litla-morao

Fumana moriana o "Gynestril" hangata e etsa hore litla joalo lehlakoreng e le hlooho e opang, ho nyekoa ke pelo, ho tsekela, ho hlatsa, lekhopho, letšollo, amenorrhea, lohiometra spotting, subinvoljutcija uterine, hyperthermia, emmeniopathy, bofokoli, ho tepella maikutlo ea ho ruruha ea popelo le appendages, boemong bo sa thabiseng le bohloko mpeng ya. Haeba u e-ba le matšoao ana, le be le bonnete ba hore a bale ngaka.

ditshebeditsano lithethefatsi

E sa kgothaletswa ho nka lithethefatsi "Gynestril" ka e tšoanang le NSAIDs. Ho lokela ho hlokomeloe hore hammoho le glucocorticoids ke ho hlokahala hore ho eketsa lethal dose ya, empa feela ka mor'a hore rerisane ngaka ya hao.

likhothaletso itseng

E sa kgothaletswa ho nka moriana ka dithibela kamehla.

Ha u sebelisa "Gynestril" Ho Ntša Mpa lokela ho lula tsebisa mokuli ka dikgetho tse ling tsa Tsamaiso ena, haholo-holo haeba ka mor'a libeke tse peli ya ho ima e tsoela pele kapa ho na le ho ntša mpa fella (khoneha kotsing ea tsela e sa tloaelehang ka ho lesea la).

Theko le analogues chelete

Analogs "Gynestril tsamaiso" ea moriana ke meriana e latelang: "Ginepriston", "Penkrofton", "Agesta" "Mifepristone", "Zhenale", "Mifolian", "Mifegin", "Mifepreks", "Miropriston".

Theko nkoa lithethefatsi e phahameng haholo le tšoana le ho 5000-6000 li-ruble.

Reviews of moriana o

Ferekanye le itseng o positive kapa mpe maikutlo mabapi le "Gynestril" ha ho na ho lokisetsa. Leha ho le joalo, bakuli ba ho fetisisa ba amohela 'nete ka sesebelisoa sena. Ba pheha khang ea hore e le e atlehang haholo le batlang e le sireletsehileng bakeng sa baeti ba fihlelang ho le.

Ho lokela ho hlokomeloe hore batho ba bang ba, ho fapana le hoo, ba atisa ho a hlokomela ka tsoelo-pele ea litla-morao.

ulasan pelanggan tsena tsohle li bontša hore ho ja ya meriana ena lokela ho etsoa feela ka mor'a hore a buisane le ngaka.