Lipid-theola lithethefatsi "Rosuvastatin": litaelo tsa tšebeliso

Medicine "Rosuvastatin" taeo pukwanana hlalosang e le hypolipidemic lithethefatsi tsa statins. Tshebetso ea mokhoa ona khetha ke tlhōlisano thibelo ea HMG-CoA reductase. Tshebediso ya ba lokisetsa ho ea "Rosuvastatin" (litaelo bakeng sa ho sebelisoa e tiisa) ka makhetlo a 'maloa e ile ea eketseha LDL catabolism, e ile ea eketseha lebelo la receptors e amanang le sebete LDL le ka tjhelete e ya VLDL fokotsehile. Ha e le thepa pharmacokinetic ea lithethefatsi le lipid-theola, ho bitsoa phekolo phello ea baeti ba fihlelang ho sona o ile a re ka matsatsi a supileng ka mor'a ho qala ha phekolo, fihla lebaka lona ka ho fetisisa tsa libeke tse 'nè.

Nka pilisi e "Rosuvastatin" moetsi e khothalletsa hore batho ba nang le mofuta o le e tsoakiloeng ba hypercholesterolemia (thaepa IIb) hypercholesterolaemia kapa IIa (ho akarelletsa le heterozygous) e le adjunct ho ja lijo.

Kahoo bokgoni phahameng ka ho fetisisa hypolipidemic a sebetsang a lithethefatsi e joalo ha kalafo mekhoa e meng (ikoetlisa, phokotso ea boima ba 'mele) se etsa hore bakeng sa ho fihlela ka lebaka tšoanetseng phekolo. Ho feta moo, sebelisa khetha moemeli "Rosuvastatin" taeo pukwanana buella e le lithethefatsi ba thusang nakong phekolo homozygous mofuta hypercholesterolemia lelapa.

Abela matlapa ana e tieo hanetsoeng tabeng ea mokuli oa mafu haholo sebete, myopathy kapa mafu a bontšitsoeng ka liphio le. Nakong ea bokhachane, le eena o lokela ho nka lipid-theola lithethefatsi "Rosuvastatin." moriana o contraindicated ka nako ea diabolololo. Ho feta moo, e sa kgothaletswa ho nka matlapa ana concurrently le cyclosporine kapa hypersensitivity ho dikarolo tsa bona. Batho ba sa kang ba fumana a le lilemo li leshome le metso e robeli, 'me ho ke ke ha hlokahala hore a khethe e le moemeli khetha "Rosuvastatin." Litaelo bakeng sa ho sebelisoa ha ba eletswa ho nka e le tabeng ea ho itšetleha joala thehilwe renal ho hloleha kapa sebete le mafu.

Ka hloko haholo ho sebelisa lithethefatsi le lipid-theola e lokela ho ba batho ba utloa bohloko electrolyte, endocrine le tshilong ya dijo ka mafu a, hypothyroidism kapa hypotension. Ka sepsis, laoleheng sethoathoa, proteinuria, ho sithabela ka sehloohong le tsereletsi ho buoa hape ba lokela ho ba khaotse ho ho nka lithethefatsi, "Rosuvastatin." Ho phaella moo, contraindications a lekanyelitsoeng ke mafu a lefa mesifa le lilemo a le moholo ho lilemo tse mashome a tšeletseng a metso e mehlano.

Qetellong, e lokela ho ile a re ka ho khoneha liphetoho e bohloko, e leng ketsahalo e sa leng e ka bakoa ke ea moketeng oa lijo e bolela "Rosuvastatin." Mohlala, bakuli ba bangata ba tletleba ka ya bohloko mpeng, pipitlelano, ho tsekela le ho nyekoa ke pelo. Ho phaella moo, ho na le kotsi e kaalo ea myopathy, proteinuria, asthenia , le myalgia.